There is a long list of 191 institutional holders of SWTX within the last two holding periods in our database of 13F filers, so we've sorted through to present to you just the top 50 institutional holders of SWTX by largest to smallest position reported in the institutional investor's latest 13F filing. In the institutional-holders-of-SWTX table below, the initial column indicates the name of each top institutional holder of SWTX, with a link to that fund's top holdings. The next columns indicate the amount of SWTX stock held by each of the institutional holders of SWTX, followed by the SWTX position size held by the institution, and finally the date of the quarterly 13F filing period the holdings data represents for that institution.

Holder	Amount	Position Size ($ in 1000's)	As of
FMR LLC	10,809,235	$394,537	12/31/2023
SWTX	10,809,235	$394,537	12/31/2023
Vanguard Group Inc.	6,036,542	$220,334	12/31/2023
SWTX	6,036,542	$220,334	12/31/2023
BlackRock Inc.	5,382,184	$196,450	12/31/2023
SWTX	5,382,184	$196,450	12/31/2023
Deep Track Capital LP	4,063,676	$148,324	12/31/2023
SWTX	4,063,676	$148,324	12/31/2023
Boxer Capital LLC	3,421,541	$124,886	12/31/2023
SWTX	3,421,541	$124,886	12/31/2023
Orbimed Advisors LLC	3,219,359	$117,507	12/31/2023
SWTX	3,219,359	$117,507	12/31/2023
Marshall Wace LLP	3,024,859	$110,407	12/31/2023
SWTX	3,024,859	$110,407	12/31/2023
Maverick Capital Ltd.	2,873,216	$104,872	12/31/2023
SWTX	2,873,216	$104,872	12/31/2023
Price T Rowe Associates Inc. MD	2,776,570	$101,346	12/31/2023
SWTX	2,776,570	$101,346	12/31/2023
State Street Corp	2,619,650	$95,617	12/31/2023
SWTX	2,619,650	$95,617	12/31/2023
Deerfield Management Company L.P. Series C	2,584,376	$94,330	12/31/2023
SWTX	2,584,376	$94,330	12/31/2023
Point72 Asset Management L.P.	2,162,176	$78,919	12/31/2023
SWTX	2,162,176	$78,919	12/31/2023
ArrowMark Colorado Holdings LLC	2,096,808	$76,533	12/31/2023
SWTX	2,096,808	$76,533	12/31/2023
Perceptive Advisors LLC	1,957,246	$71,439	12/31/2023
SWTX	1,957,246	$71,439	12/31/2023
Artal Group S.A.	1,615,348	$58,960	12/31/2023
SWTX	1,615,348	$58,960	12/31/2023
Pictet Asset Management Holding SA	1,558,487	$56,885	12/31/2023
SWTX	1,558,487	$56,885	12/31/2023
Geode Capital Management LLC	1,419,088	$51,802	12/31/2023
SWTX	1,419,088	$51,802	12/31/2023
Dimensional Fund Advisors LP	968,405	$35,348	12/31/2023
SWTX	968,405	$35,348	12/31/2023
Fiera Capital Corp	893,456	$32,611	12/31/2023
SWTX	893,456	$32,611	12/31/2023
Woodline Partners LP	802,182	$29,280	12/31/2023
SWTX	802,182	$29,280	12/31/2023
RTW Investments LP	625,000	$22,812	12/31/2023
SWTX	625,000	$22,812	12/31/2023
JPMorgan Chase & Co.	615,222	$22,456	12/31/2023
SWTX	615,222	$22,456	12/31/2023
Northern Trust Corp	591,382	$21,585	12/31/2023
SWTX	591,382	$21,585	12/31/2023
Morgan Stanley	570,664	$20,829	12/31/2023
SWTX	570,664	$20,829	12/31/2023
Finepoint Capital LP	556,928	$20,328	12/31/2023
SWTX	556,928	$20,328	12/31/2023
Ameriprise Financial Inc.	520,255	$18,989	12/31/2023
SWTX	520,255	$18,989	12/31/2023
Charles Schwab Investment Management Inc.	501,067	$18,289	12/31/2023
SWTX	501,067	$18,289	12/31/2023
Voloridge Investment Management LLC	500,749	$18,277	12/31/2023
SWTX	500,749	$18,277	12/31/2023
Massachusetts Financial Services Co. MA	468,078	$17,085	12/31/2023
SWTX	468,078	$17,085	12/31/2023
Schonfeld Strategic Advisors LLC	466,457	$17,026	12/31/2023
SWTX	466,457	$17,026	12/31/2023
Goldman Sachs Group Inc.	461,275	$16,837	12/31/2023
SWTX	461,275	$16,837	12/31/2023
Citadel Advisors LLC		$15,129	12/31/2023
SWTX	417,814	$15,250	12/31/2023
Put	38,100	$1,391	12/31/2023
Call	34,800	$1,270	12/31/2023
Oracle Investment Management Inc.		$14,859	12/31/2023
Call	250,000	$9,125	12/31/2023
SWTX	157,083	$5,734	12/31/2023
Laurion Capital Management LP	372,074	$13,581	12/31/2023
SWTX	372,074	$13,581	12/31/2023
Victory Capital Management Inc.	369,367	$13,482	12/31/2023
SWTX	369,367	$13,482	12/31/2023
Bank of America Corp DE	355,348	$12,970	12/31/2023
SWTX	355,348	$12,970	12/31/2023
Checkpoint Capital L.P.	340,000	$12,410	12/31/2023
SWTX	340,000	$12,410	12/31/2023
Caption Management LLC		$12,333	12/31/2023
Call	337,900	$12,333	12/31/2023
Norges Bank	337,833	$12,331	12/31/2023
SWTX	337,833	$12,331	12/31/2023
Bank of New York Mellon Corp	232,800	$11,458	03/31/2024
SWTX	232,800	$11,458	03/31/2024
Jefferies Financial Group Inc.		$11,438	12/31/2023
SWTX	356,078	$12,997	12/31/2023
Put	42,700	$1,559	12/31/2023
Candriam Luxembourg S.C.A.	275,628	$10,061	12/31/2023
SWTX	275,628	$10,061	12/31/2023
New York State Common Retirement Fund	253,741	$9,262	12/31/2023
SWTX	253,741	$9,262	12/31/2023
Bessemer Group Inc.	241,337	$8,809	12/31/2023
SWTX	241,337	$8,809	12/31/2023
Darwin Global Management Ltd.	192,734	$7,035	12/31/2023
SWTX	192,734	$7,035	12/31/2023
Nuveen Asset Management LLC	184,146	$6,721	12/31/2023
SWTX	184,146	$6,721	12/31/2023
TD Asset Management Inc.	181,432	$6,622	12/31/2023
SWTX	181,432	$6,622	12/31/2023
Susquehanna International Group LLP		$6,426	12/31/2023
SWTX	130,659	$4,769	12/31/2023
Call	91,900	$3,354	12/31/2023
Put	46,500	$1,697	12/31/2023
Sphera Funds Management LTD.	170,270	$6,215	12/31/2023
SWTX	170,270	$6,215	12/31/2023
Jane Street Group LLC		$5,986	12/31/2023
SWTX	121,596	$4,438	12/31/2023
Call	56,000	$2,044	12/31/2023
Put	13,600	$496	12/31/2023