There is a long list of 162 institutional holders of ARDX within the last two holding periods in our database of 13F filers, so we've sorted through to present to you just the top 50 institutional holders of ARDX by largest to smallest position reported in the institutional investor's latest 13F filing. In the institutional-holders-of-ARDX table below, the initial column indicates the name of each top institutional holder of ARDX, with a link to that fund's top holdings. The next columns indicate the amount of ARDX stock held by each of the institutional holders of ARDX, followed by the ARDX position size held by the institution, and finally the date of the quarterly 13F filing period the holdings data represents for that institution.

Holder	Amount	Position Size ($ in 1000's)	As of
Janus Henderson Group PLC	24,658,820	$152,777	12/31/2023
ARDX	24,658,820	$152,777	12/31/2023
State Street Corp	17,102,598	$106,036	12/31/2023
ARDX	17,102,598	$106,036	12/31/2023
BlackRock Inc.	16,776,055	$104,012	12/31/2023
ARDX	16,776,055	$104,012	12/31/2023
Vanguard Group Inc.	13,026,046	$80,761	12/31/2023
ARDX	13,026,046	$80,761	12/31/2023
Eventide Asset Management LLC	6,805,494	$42,194	12/31/2023
ARDX	6,805,494	$42,194	12/31/2023
Geode Capital Management LLC	4,995,362	$30,975	12/31/2023
ARDX	4,995,362	$30,975	12/31/2023
Rubric Capital Management LP	4,012,753	$24,879	12/31/2023
ARDX	4,012,753	$24,879	12/31/2023
Morgan Stanley	3,205,108	$19,872	12/31/2023
ARDX	3,205,108	$19,872	12/31/2023
Adage Capital Partners GP L.L.C.	2,600,000	$16,120	12/31/2023
ARDX	2,600,000	$16,120	12/31/2023
Susquehanna International Group LLP		$15,862	12/31/2023
ARDX	2,589,482	$16,055	12/31/2023
Put	720,000	$4,464	12/31/2023
Call	688,900	$4,271	12/31/2023
Invesco Ltd.	2,333,127	$14,465	12/31/2023
ARDX	2,333,127	$14,465	12/31/2023
Price T Rowe Associates Inc. MD	2,329,266	$14,442	12/31/2023
ARDX	2,329,266	$14,442	12/31/2023
Oracle Investment Management Inc.		$14,196	12/31/2023
Call	1,425,000	$8,835	12/31/2023
ARDX	864,700	$5,361	12/31/2023
Northern Trust Corp	2,187,818	$13,564	12/31/2023
ARDX	2,187,818	$13,564	12/31/2023
Barclays PLC	2,185,620	$13,552	12/31/2023
ARDX	2,185,620	$13,552	12/31/2023
Nuveen Asset Management LLC	2,107,891	$13,069	12/31/2023
ARDX	2,107,891	$13,069	12/31/2023
Charles Schwab Investment Management Inc.	1,816,732	$11,264	12/31/2023
ARDX	1,816,732	$11,264	12/31/2023
J. Goldman & Co LP	1,599,220	$9,915	12/31/2023
ARDX	1,599,220	$9,915	12/31/2023
Knott David M Jr	1,380,000	$8,556	12/31/2023
ARDX	1,380,000	$8,556	12/31/2023
Rafferty Asset Management LLC	1,375,514	$8,528	12/31/2023
ARDX	1,375,514	$8,528	12/31/2023
Lion Point Capital LP	1,151,667	$7,140	12/31/2023
ARDX	1,151,667	$7,140	12/31/2023
Bank of New York Mellon Corp	965,763	$7,050	03/31/2024
ARDX	965,763	$7,050	03/31/2024
Voloridge Investment Management LLC	1,137,068	$7,050	12/31/2023
ARDX	1,137,068	$7,050	12/31/2023
Deutsche Bank AG	1,133,147	$7,026	12/31/2023
ARDX	1,133,147	$7,026	12/31/2023
Goldman Sachs Group Inc.	1,104,070	$6,845	12/31/2023
ARDX	1,104,070	$6,845	12/31/2023
Standard Life Aberdeen plc	833,614	$5,168	12/31/2023
ARDX	833,614	$5,168	12/31/2023
Pekin Hardy Strauss Inc.	771,367	$4,782	12/31/2023
ARDX	771,367	$4,782	12/31/2023
BNP Paribas Arbitrage SA	644,975	$3,999	12/31/2023
ARDX	644,975	$3,999	12/31/2023
UBS Group AG	598,650	$3,712	12/31/2023
ARDX	598,650	$3,712	12/31/2023
Propel Bio Management LLC	594,174	$3,684	12/31/2023
ARDX	594,174	$3,684	12/31/2023
Jane Street Group LLC		$3,663	12/31/2023
ARDX	1,095,906	$6,795	12/31/2023
Put	725,200	$4,496	12/31/2023
Call	220,000	$1,364	12/31/2023
Citigroup Inc.	555,576	$3,445	12/31/2023
ARDX	555,576	$3,445	12/31/2023
Hennion & Walsh Asset Management Inc.	438,827	$3,203	03/31/2024
ARDX	438,827	$3,203	03/31/2024
Voya Investment Management LLC	505,853	$3,136	12/31/2023
ARDX	505,853	$3,136	12/31/2023
Two Sigma Investments LP	469,293	$2,910	12/31/2023
ARDX	469,293	$2,910	12/31/2023
Swiss National Bank	429,400	$2,662	12/31/2023
ARDX	429,400	$2,662	12/31/2023
Group One Trading L.P.		$2,548	12/31/2023
Call	589,000	$3,652	12/31/2023
Put	572,000	$3,546	12/31/2023
ARDX	393,805	$2,442	12/31/2023
JPMorgan Chase & Co.	354,257	$2,196	12/31/2023
ARDX	354,257	$2,196	12/31/2023
Simplify Asset Management Inc.	350,000	$2,170	12/31/2023
ARDX	350,000	$2,170	12/31/2023
Rhumbline Advisers	326,764	$2,026	12/31/2023
ARDX	326,764	$2,026	12/31/2023
Squarepoint Ops LLC	326,289	$2,023	12/31/2023
ARDX	326,289	$2,023	12/31/2023
UBS Asset Management Americas Inc.	310,646	$1,926	12/31/2023
ARDX	310,646	$1,926	12/31/2023
TD Asset Management Inc.	290,936	$1,804	12/31/2023
ARDX	290,936	$1,804	12/31/2023
New York State Common Retirement Fund	283,648	$1,759	12/31/2023
ARDX	283,648	$1,759	12/31/2023
683 Capital Management LLC	272,000	$1,686	12/31/2023
ARDX	272,000	$1,686	12/31/2023
Russell Investments Group Ltd.	267,251	$1,657	12/31/2023
ARDX	267,251	$1,657	12/31/2023
Credit Suisse AG	266,336	$1,651	12/31/2023
ARDX	266,336	$1,651	12/31/2023
Dimensional Fund Advisors LP	256,956	$1,594	12/31/2023
ARDX	256,956	$1,594	12/31/2023
Simplex Trading LLC		$1,583	03/31/2024
Call	350,900	$2,561	03/31/2024
Put	276,700	$2,019	03/31/2024
ARDX	142,649	$1,041	03/31/2024
The Manufacturers Life Insurance Company	238,393	$1,478	12/31/2023
ARDX	238,393	$1,478	12/31/2023