There is a long list of 105 institutional holders of ACRS within the last two holding periods in our database of 13F filers, so we've sorted through to present to you just the top 50 institutional holders of ACRS by largest to smallest position reported in the institutional investor's latest 13F filing. In the institutional-holders-of-ACRS table below, the initial column indicates the name of each top institutional holder of ACRS, with a link to that fund's top holdings. The next columns indicate the amount of ACRS stock held by each of the institutional holders of ACRS, followed by the ACRS position size held by the institution, and finally the date of the quarterly 13F filing period the holdings data represents for that institution.

Holder	Amount	Position Size ($ in 1000's)	As of
BML Capital Management LLC	9,395,934	$11,651	03/31/2024
ACRS	9,395,934	$11,651	03/31/2024
BlackRock Inc.	5,905,872	$6,201	12/31/2023
ACRS	5,905,872	$6,201	12/31/2023
Citadel Advisors LLC		$5,641	12/31/2023
ACRS	5,388,789	$5,658	12/31/2023
Put	33,500	$35	12/31/2023
Call	17,300	$18	12/31/2023
Vanguard Group Inc.	4,722,357	$4,958	12/31/2023
ACRS	4,722,357	$4,958	12/31/2023
Bain Capital Life Sciences Investors LLC	3,500,000	$3,675	12/31/2023
ACRS	3,500,000	$3,675	12/31/2023
Millennium Management LLC	3,479,361	$3,653	12/31/2023
ACRS	3,479,361	$3,653	12/31/2023
Rock Springs Capital Management LP	2,998,495	$3,148	12/31/2023
ACRS	2,998,495	$3,148	12/31/2023
Acadian Asset Management LLC	2,351,407	$2,467	12/31/2023
ACRS	2,351,407	$2,467	12/31/2023
D. E. Shaw & Co. Inc.	1,939,010	$2,036	12/31/2023
ACRS	1,939,010	$2,036	12/31/2023
Velan Capital Investment Management LP	1,761,595	$1,850	12/31/2023
ACRS	1,761,595	$1,850	12/31/2023
Tang Capital Management LLC	1,753,335	$1,841	12/31/2023
ACRS	1,753,335	$1,841	12/31/2023
Renaissance Technologies LLC	1,746,432	$1,834	12/31/2023
ACRS	1,746,432	$1,834	12/31/2023
Qube Research & Technologies Ltd	1,679,905	$1,764	12/31/2023
ACRS	1,679,905	$1,764	12/31/2023
GSA Capital Partners LLP	1,587,995	$1,667	12/31/2023
ACRS	1,587,995	$1,667	12/31/2023
Two Sigma Investments LP	1,463,461	$1,537	12/31/2023
ACRS	1,463,461	$1,537	12/31/2023
Two Sigma Advisers LP	1,421,000	$1,492	12/31/2023
ACRS	1,421,000	$1,492	12/31/2023
Geode Capital Management LLC	1,393,548	$1,463	12/31/2023
ACRS	1,393,548	$1,463	12/31/2023
State Street Corp	1,388,439	$1,458	12/31/2023
ACRS	1,388,439	$1,458	12/31/2023
Monaco Asset Management SAM	979,399	$1,028	12/31/2023
ACRS	979,399	$1,028	12/31/2023
Morgan Stanley	975,879	$1,025	12/31/2023
ACRS	975,879	$1,025	12/31/2023
Deutsche Bank AG	934,046	$981	12/31/2023
ACRS	934,046	$981	12/31/2023
Jacobs Levy Equity Management Inc.	748,775	$786	12/31/2023
ACRS	748,775	$786	12/31/2023
Samsara BioCapital LLC	696,171	$731	12/31/2023
ACRS	696,171	$731	12/31/2023
FMR LLC	670,714	$704	12/31/2023
ACRS	670,714	$704	12/31/2023
Northern Trust Corp	659,637	$693	12/31/2023
ACRS	659,637	$693	12/31/2023
Goldman Sachs Group Inc.	520,880	$547	12/31/2023
ACRS	520,880	$547	12/31/2023
Citigroup Inc.	507,508	$533	12/31/2023
ACRS	507,508	$533	12/31/2023
Checkpoint Capital L.P.	453,614	$476	12/31/2023
ACRS	453,614	$476	12/31/2023
Nuveen Asset Management LLC	439,901	$462	12/31/2023
ACRS	439,901	$462	12/31/2023
Charles Schwab Investment Management Inc.	436,330	$458	12/31/2023
ACRS	436,330	$458	12/31/2023
Aisling Capital Management LP	434,455	$456	12/31/2023
ACRS	434,455	$456	12/31/2023
XTX Topco Ltd	378,300	$397	12/31/2023
ACRS	378,300	$397	12/31/2023
HighTower Advisors LLC	343,024	$361	12/31/2023
ACRS	343,024	$361	12/31/2023
Bank of New York Mellon Corp	232,771	$289	03/31/2024
ACRS	232,771	$289	03/31/2024
Frazier Life Sciences Management L.P.	264,377	$278	12/31/2023
ACRS	264,377	$278	12/31/2023
Jane Street Group LLC	259,384	$272	12/31/2023
ACRS	259,384	$272	12/31/2023
BNP Paribas Arbitrage SA	217,354	$228	12/31/2023
ACRS	217,354	$228	12/31/2023
Strs Ohio	193,000	$202	12/31/2023
ACRS	193,000	$202	12/31/2023
Dimensional Fund Advisors LP	187,553	$197	12/31/2023
ACRS	187,553	$197	12/31/2023
Barclays PLC	175,919	$184	12/31/2023
ACRS	175,919	$184	12/31/2023
Susquehanna International Group LLP		$172	12/31/2023
ACRS	153,609	$161	12/31/2023
Call	32,800	$34	12/31/2023
Put	22,100	$23	12/31/2023
Endurant Capital Management LP	148,400	$156	12/31/2023
ACRS	148,400	$156	12/31/2023
Credit Suisse AG	135,629	$142	12/31/2023
ACRS	135,629	$142	12/31/2023
Cubist Systematic Strategies LLC	135,295	$142	12/31/2023
ACRS	135,295	$142	12/31/2023
Bank of America Corp DE	125,387	$132	12/31/2023
ACRS	125,387	$132	12/31/2023
Lion Point Capital LP	115,898	$122	12/31/2023
ACRS	115,898	$122	12/31/2023
UBS Asset Management Americas Inc.	113,601	$119	12/31/2023
ACRS	113,601	$119	12/31/2023
Price T Rowe Associates Inc. MD	108,515	$114	12/31/2023
ACRS	108,515	$114	12/31/2023
Swiss National Bank	108,900	$114	12/31/2023
ACRS	108,900	$114	12/31/2023
Man Group plc	101,280	$106	12/31/2023
ACRS	101,280	$106	12/31/2023