On this page, we present all of the funds holding REPL from our database of 13F filers, detailed in the table below. The first column indicates the name of each of the funds holding REPL, with a link to that fund's top holdings. The next columns indicate the amount of REPL stock held by each of the funds holding REPL, followed by the REPL position size held by the fund, and lastly the date of the quarterly filing period the data represents. In total, we count 145 funds holding REPL within the last two filing periods in our coverage universe of 13F filers, with the largest position size having been reported by Baker BROS. Advisors LP. For more details on the positions held by Baker BROS. Advisors LP (or by any of the other funds holding REPL), click the fund name in the "Holder" column of the funds-holding-REPL table below.

Holder	Amount	Position Size ($ in 1000's)	As of
Baker BROS. Advisors LP	9,545,336	$80,467	12/31/2023
REPL	9,545,336	$80,467	12/31/2023
Price T Rowe Associates Inc. MD	5,849,251	$49,310	12/31/2023
REPL	5,849,251	$49,310	12/31/2023
State Street Corp	5,111,521	$43,090	12/31/2023
REPL	5,111,521	$43,090	12/31/2023
Fcpm Iii Services B.V.	4,866,499	$41,024	12/31/2023
REPL	4,866,499	$41,024	12/31/2023
BlackRock Inc.	4,538,487	$38,259	12/31/2023
REPL	4,538,487	$38,259	12/31/2023
Morgan Stanley	4,447,228	$37,490	12/31/2023
REPL	4,447,228	$37,490	12/31/2023
Redmile Group LLC	3,865,258	$32,584	12/31/2023
REPL	3,865,258	$32,584	12/31/2023
Omega Fund Management LLC	3,001,319	$25,301	12/31/2023
REPL	3,001,319	$25,301	12/31/2023
Vanguard Group Inc.	2,737,773	$23,079	12/31/2023
REPL	2,737,773	$23,079	12/31/2023
Goldman Sachs Group Inc.	2,238,883	$18,874	12/31/2023
REPL	2,238,883	$18,874	12/31/2023
Atlas Venture Life Science Advisors LLC	2,098,300	$17,689	12/31/2023
REPL	2,098,300	$17,689	12/31/2023
Deerfield Management Company L.P. Series C	1,811,710	$15,273	12/31/2023
REPL	1,811,710	$15,273	12/31/2023
Dimensional Fund Advisors LP	1,322,969	$11,153	12/31/2023
REPL	1,322,969	$11,153	12/31/2023
Geode Capital Management LLC	1,145,112	$9,654	12/31/2023
REPL	1,145,112	$9,654	12/31/2023
Camber Capital Management LP	1,000,000	$8,430	12/31/2023
REPL	1,000,000	$8,430	12/31/2023
FMR LLC	825,861	$6,962	12/31/2023
REPL	825,861	$6,962	12/31/2023
Emerald Advisers LLC	538,841	$4,542	12/31/2023
REPL	538,841	$4,542	12/31/2023
Artal Group S.A.	500,000	$4,215	12/31/2023
REPL	500,000	$4,215	12/31/2023
Northern Trust Corp	481,834	$4,062	12/31/2023
REPL	481,834	$4,062	12/31/2023
Rafferty Asset Management LLC	463,397	$3,906	12/31/2023
REPL	463,397	$3,906	12/31/2023
Charles Schwab Investment Management Inc.	401,942	$3,388	12/31/2023
REPL	401,942	$3,388	12/31/2023
Ghost Tree Capital LLC	400,000	$3,372	12/31/2023
REPL	400,000	$3,372	12/31/2023
Qube Research & Technologies Ltd	394,716	$3,327	12/31/2023
REPL	394,716	$3,327	12/31/2023
Emerald Mutual Fund Advisers Trust	347,410	$2,929	12/31/2023
REPL	347,410	$2,929	12/31/2023
Canada Pension Plan Investment Board	319,000	$2,689	12/31/2023
REPL	319,000	$2,689	12/31/2023
Sectoral Asset Management Inc	305,412	$2,575	12/31/2023
REPL	305,412	$2,575	12/31/2023
Vontobel Holding Ltd.	305,412	$2,575	12/31/2023
REPL	305,412	$2,575	12/31/2023
JPMorgan Chase & Co.	305,023	$2,571	12/31/2023
REPL	305,023	$2,571	12/31/2023
Woodline Partners LP	293,622	$2,475	12/31/2023
REPL	293,622	$2,475	12/31/2023
Barclays PLC	290,504	$2,449	12/31/2023
REPL	290,504	$2,449	12/31/2023
Clearbridge Investments LLC	270,695	$2,282	12/31/2023
REPL	270,695	$2,282	12/31/2023
Ensign Peak Advisors Inc	270,007	$2,276	12/31/2023
REPL	270,007	$2,276	12/31/2023
TD Asset Management Inc.	267,646	$2,256	12/31/2023
REPL	267,646	$2,256	12/31/2023
Jane Street Group LLC		$2,235	12/31/2023
REPL	243,512	$2,053	12/31/2023
Call	43,900	$370	12/31/2023
Put	22,300	$188	12/31/2023
Wellington Management Group LLP	246,624	$2,079	12/31/2023
REPL	246,624	$2,079	12/31/2023
D. E. Shaw & Co. Inc.	243,006	$2,049	12/31/2023
REPL	243,006	$2,049	12/31/2023
Bank of America Corp DE	220,647	$1,860	12/31/2023
REPL	220,647	$1,860	12/31/2023
UBS Group AG	220,427	$1,858	12/31/2023
REPL	220,427	$1,858	12/31/2023
Two Sigma Advisers LP	202,700	$1,709	12/31/2023
REPL	202,700	$1,709	12/31/2023
BNP Paribas Arbitrage SA	196,251	$1,654	12/31/2023
REPL	196,251	$1,654	12/31/2023
Amundi	174,448	$1,624	12/31/2023
REPL	174,448	$1,624	12/31/2023
Nan Fung Group Holdings Ltd	184,739	$1,557	12/31/2023
REPL	184,739	$1,557	12/31/2023
Citigroup Inc.	183,261	$1,545	12/31/2023
REPL	183,261	$1,545	12/31/2023
Connor Clark & Lunn Investment Management Ltd.	180,442	$1,521	12/31/2023
REPL	180,442	$1,521	12/31/2023
ExodusPoint Capital Management LP	164,222	$1,384	12/31/2023
REPL	164,222	$1,384	12/31/2023
Bank of New York Mellon Corp	162,755	$1,330	03/31/2024
REPL	162,755	$1,330	03/31/2024
The Manufacturers Life Insurance Company	154,748	$1,305	12/31/2023
REPL	154,748	$1,305	12/31/2023
Citadel Advisors LLC		$1,286	12/31/2023
REPL	207,537	$1,750	12/31/2023
Put	72,600	$612	12/31/2023
Call	17,600	$148	12/31/2023
Deutsche Bank AG	137,779	$1,161	12/31/2023
REPL	137,779	$1,161	12/31/2023
Nuveen Asset Management LLC	116,987	$986	12/31/2023
REPL	116,987	$986	12/31/2023
Two Sigma Investments LP	114,182	$963	12/31/2023
REPL	114,182	$963	12/31/2023
UBS Oconnor LLC	100,000	$843	12/31/2023
REPL	100,000	$843	12/31/2023
Marshall Wace LLP	96,834	$816	12/31/2023
REPL	96,834	$816	12/31/2023
Fisher Asset Management LLC	77,663	$655	12/31/2023
REPL	77,663	$655	12/31/2023
Rhumbline Advisers	77,165	$650	12/31/2023
REPL	77,165	$650	12/31/2023
Landscape Capital Management L.L.C.	76,869	$648	12/31/2023
REPL	76,869	$648	12/31/2023
Profund Advisors LLC	74,233	$626	12/31/2023
REPL	74,233	$626	12/31/2023
Anson Funds Management LP	73,228	$617	12/31/2023
REPL	73,228	$617	12/31/2023
Swiss National Bank	69,800	$588	12/31/2023
REPL	69,800	$588	12/31/2023
LMR Partners LLP		$549	12/31/2023
Call	65,100	$549	12/31/2023
REPL	1	$0	12/31/2023
Los Angeles Capital Management & Equity Research Inc.	66,405	$543	03/31/2024
REPL	66,405	$543	03/31/2024
Algert Global LLC	63,973	$539	12/31/2023
REPL	63,973	$539	12/31/2023
Prudential Financial Inc.	54,650	$461	12/31/2023
REPL	54,650	$461	12/31/2023
Graham Capital Management L.P.	50,175	$423	12/31/2023
REPL	50,175	$423	12/31/2023
Entropy Technologies LP	50,146	$423	12/31/2023
REPL	50,146	$423	12/31/2023
Alliancebernstein L.P.	46,730	$394	12/31/2023
REPL	46,730	$394	12/31/2023
Lion Point Capital LP	42,500	$358	12/31/2023
REPL	42,500	$358	12/31/2023
Schonfeld Strategic Advisors LLC	42,394	$357	12/31/2023
REPL	42,394	$357	12/31/2023
Mirae Asset Global Investments Co. Ltd.	40,223	$339	12/31/2023
REPL	40,223	$339	12/31/2023
California State Teachers Retirement System	39,685	$335	12/31/2023
REPL	39,685	$335	12/31/2023
Alps Advisors Inc.	39,774	$335	12/31/2023
REPL	39,774	$335	12/31/2023
Walleye Capital LLC		$335	12/31/2023
REPL	30,058	$253	12/31/2023
Call	10,700	$90	12/31/2023
Put	1,000	$8	12/31/2023
Credit Suisse AG	37,859	$319	12/31/2023
REPL	37,859	$319	12/31/2023
Denali Advisors LLC	36,300	$297	03/31/2024
REPL	36,300	$297	03/31/2024
Legal & General Group Plc	34,742	$293	12/31/2023
REPL	34,742	$293	12/31/2023
Renaissance Technologies LLC	33,853	$285	12/31/2023
REPL	33,853	$285	12/31/2023
American Century Companies Inc.	32,866	$277	12/31/2023
REPL	32,866	$277	12/31/2023
Harbor Capital Advisors Inc.	32,311	$272	12/31/2023
REPL	32,311	$272	12/31/2023
Exchange Traded Concepts LLC	32,232	$263	03/31/2024
REPL	32,232	$263	03/31/2024
Pennant Investors LP	30,500	$257	12/31/2023
REPL	30,500	$257	12/31/2023
EntryPoint Capital LLC	29,862	$252	12/31/2023
REPL	29,862	$252	12/31/2023
State of Wisconsin Investment Board	29,622	$250	12/31/2023
REPL	29,622	$250	12/31/2023
MetLife Investment Management LLC	26,645	$225	12/31/2023
REPL	26,645	$225	12/31/2023
Cornercap Investment Counsel Inc.	26,493	$223	12/31/2023
REPL	26,493	$223	12/31/2023
E Fund Management Co. Ltd.	24,739	$209	12/31/2023
REPL	24,739	$209	12/31/2023
American International Group Inc.	24,577	$207	12/31/2023
REPL	24,577	$207	12/31/2023
Hsbc Holdings PLC	23,532	$195	12/31/2023
REPL	23,532	$195	12/31/2023
Wells Fargo & Company MN	22,389	$189	12/31/2023
REPL	22,389	$189	12/31/2023
Invesco Ltd.	22,220	$187	12/31/2023
REPL	22,220	$187	12/31/2023
Royal Bank of Canada	19,315	$163	12/31/2023
REPL	19,315	$163	12/31/2023
Voya Investment Management LLC	19,292	$163	12/31/2023
REPL	19,292	$163	12/31/2023
Janus Henderson Group PLC	17,963	$152	12/31/2023
REPL	17,963	$152	12/31/2023
AQR Capital Management LLC	17,825	$150	12/31/2023
REPL	17,825	$150	12/31/2023
Squarepoint Ops LLC	17,716	$149	12/31/2023
REPL	17,716	$149	12/31/2023
Sphera Funds Management LTD.	16,096	$136	12/31/2023
REPL	16,096	$136	12/31/2023
Millennium Management LLC	15,026	$127	12/31/2023
REPL	15,026	$127	12/31/2023
Principal Financial Group Inc.	14,700	$124	12/31/2023
REPL	14,700	$124	12/31/2023
UBS Asset Management Americas Inc.	14,380	$121	12/31/2023
REPL	14,380	$121	12/31/2023
Horizon Kinetics Asset Management LLC	14,396	$121	12/31/2023
REPL	14,396	$121	12/31/2023
Captrust Financial Advisors	13,204	$111	12/31/2023
REPL	13,204	$111	12/31/2023
State Board of Administration of Florida Retirement System	12,844	$108	12/31/2023
REPL	12,844	$108	12/31/2023
ProShare Advisors LLC	11,959	$101	12/31/2023
REPL	11,959	$101	12/31/2023
Handelsbanken Fonder AB	12,000	$101	12/31/2023
REPL	12,000	$101	12/31/2023
Virtus ETF Advisers LLC	11,931	$101	12/31/2023
REPL	11,931	$101	12/31/2023
First Trust Advisors LP	11,803	$99	12/31/2023
REPL	11,803	$99	12/31/2023
Diversified Trust Co	11,460	$94	03/31/2024
REPL	11,460	$94	03/31/2024
683 Capital Management LLC	11,027	$93	12/31/2023
REPL	11,027	$93	12/31/2023
Bridgefront Capital LLC	10,023	$84	12/31/2023
REPL	10,023	$84	12/31/2023
Walleye Trading LLC		$83	12/31/2023
Call	6,500	$55	12/31/2023
REPL	4,163	$35	12/31/2023
Put	800	$7	12/31/2023
Quest Partners LLC	9,002	$76	12/31/2023
REPL	9,002	$76	12/31/2023
Zurcher Kantonalbank Zurich Cantonalbank	9,031	$74	03/31/2024
REPL	9,031	$74	03/31/2024
New York State Common Retirement Fund	7,393	$62	12/31/2023
REPL	7,393	$62	12/31/2023
China Universal Asset Management Co. Ltd.	6,833	$58	12/31/2023
REPL	6,833	$58	12/31/2023
Susquehanna International Group LLP		$47	12/31/2023
Put	32,700	$276	12/31/2023
Call	20,300	$171	12/31/2023
REPL	18,080	$152	12/31/2023
Great West Life Assurance Co. Can	4,393	$37	12/31/2023
REPL	4,393	$37	12/31/2023
Tower Research Capital LLC TRC	4,207	$35	12/31/2023
REPL	4,207	$35	12/31/2023
Ameritas Investment Partners Inc.	4,017	$34	12/31/2023
REPL	4,017	$34	12/31/2023
Quantbot Technologies LP	3,200	$27	12/31/2023
REPL	3,200	$27	12/31/2023
Metropolitan Life Insurance Co NY	2,616	$22	12/31/2023
REPL	2,616	$22	12/31/2023
Amalgamated Bank	1,450	$12	03/31/2024
REPL	1,450	$12	03/31/2024
Signaturefd LLC	1,419	$12	12/31/2023
REPL	1,419	$12	12/31/2023
Quadrant Capital Group LLC	837	$7	12/31/2023
REPL	837	$7	12/31/2023
Cutler Group LP		$6	03/31/2024
REPL	700	$6	03/31/2024
Put	100	$0	03/31/2024
CWM LLC	742	$6	03/31/2024
REPL	742	$6	03/31/2024
Allworth Financial LP	256	$2	03/31/2024
REPL	256	$2	03/31/2024
GAMMA Investing LLC	253	$2	03/31/2024
REPL	253	$2	03/31/2024
Daiwa Securities Group Inc.	200	$2	12/31/2023
REPL	200	$2	12/31/2023
EverSource Wealth Advisors LLC	240	$2	12/31/2023
REPL	240	$2	12/31/2023
Private Trust Co. NA	83	$1	03/31/2024
REPL	83	$1	03/31/2024
Versant Capital Management Inc	94	$1	03/31/2024
REPL	94	$1	03/31/2024
Lindbrook Capital LLC	101	$1	03/31/2024
REPL	101	$1	03/31/2024
Wolff Wiese Magana LLC	100	$1	03/31/2024
REPL	100	$1	03/31/2024
US Bancorp DE	110	$1	12/31/2023
REPL	110	$1	12/31/2023
Parallel Advisors LLC	150	$1	12/31/2023
REPL	150	$1	12/31/2023
Truvestments Capital LLC	80	$1	12/31/2023
REPL	80	$1	12/31/2023
Massmutual Trust Co. FSB ADV	51	$0	03/31/2024
REPL	51	$0	03/31/2024
Global Retirement Partners LLC	32	$0	03/31/2024
REPL	32	$0	03/31/2024
BOKF NA	15	$0	12/31/2023
REPL	15	$0	12/31/2023
The PNC Financial Services Group Inc.	16	$0	12/31/2023
REPL	16	$0	12/31/2023
Proequities Inc.		$0	12/31/2023
Put	0	$0	12/31/2023
Call	0	$0	12/31/2023
REPL	0	$0	12/31/2023
Comerica Bank	14	$0	12/31/2023
REPL	14	$0	12/31/2023
Advisor Group Holdings Inc.	30	$0	12/31/2023
REPL	30	$0	12/31/2023
Covestor Ltd	6	$0	12/31/2023
REPL	6	$0	12/31/2023
Farther Finance Advisors LLC	5	$0	12/31/2023
REPL	5	$0	12/31/2023
Simplex Trading LLC		$-227	03/31/2024
Put	43,400	$354	03/31/2024
REPL	11,641	$95	03/31/2024
Call	4,000	$32	03/31/2024
Group One Trading L.P.	28,100	$-824	12/31/2023
Put	261,100	$2,201	12/31/2023
REPL	135,243	$1,140	12/31/2023
Call	28,100	$237	12/31/2023