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Holder Amount Position Size ($ in 1000's)  As of Eventide Asset Management LLC 1,394,336 $3,249  12/31/2023      VYNE 1,394,336 $3,249  12/31/2023 Cormorant Asset Management LP 1,394,336 $3,249  12/31/2023      VYNE 1,394,336 $3,249  12/31/2023 Citadel Advisors LLC 1,181,088 $2,752  12/31/2023      VYNE 1,181,088 $2,752  12/31/2023 Soleus Capital Management L.P. 703,868 $1,640  12/31/2023      VYNE 703,868 $1,640  12/31/2023 DSC Advisors L.P. 696,465 $1,623  12/31/2023      VYNE 696,465 $1,623  12/31/2023 Parkman Healthcare Partners LLC 696,470 $1,623  12/31/2023      VYNE 696,470 $1,623  12/31/2023 AlphaCentric Advisors LLC 668,151 $1,557  12/31/2023      VYNE 668,151 $1,557  12/31/2023 Palo Alto Investors LP 445,434 $1,038  12/31/2023      VYNE 445,434 $1,038  12/31/2023 Prelude Capital Management LLC 118,100 $275  12/31/2023      VYNE 118,100 $275  12/31/2023 Exome Asset Management LLC 118,100 $275  12/31/2023      VYNE 118,100 $275  12/31/2023 Geode Capital Management LLC 94,343 $220  12/31/2023      VYNE 94,343 $220  12/31/2023 Susquehanna International Group LLP 60,323 $141  12/31/2023      VYNE 60,323 $141  12/31/2023 Fred Alger Management LLC 60,055 $140  12/31/2023      VYNE 60,055 $140  12/31/2023 Vanguard Group Inc. 49,582 $116  12/31/2023      VYNE 49,582 $116  12/31/2023 BlackRock Inc. 47,297 $110  12/31/2023      VYNE 47,297 $110  12/31/2023 Renaissance Technologies LLC 46,376 $108  12/31/2023      VYNE 46,376 $108  12/31/2023 Northern Trust Corp 36,951 $86  12/31/2023      VYNE 36,951 $86  12/31/2023 Millennium Management LLC 17,273 $40  12/31/2023      VYNE 17,273 $40  12/31/2023 State Street Corp 11,665 $27  12/31/2023      VYNE 11,665 $27  12/31/2023 HRT Financial LP 10,043 $23  12/31/2023      VYNE 10,043 $23  12/31/2023 US Bancorp DE 4,444 $10  12/31/2023      VYNE 4,444 $10  12/31/2023 Bank of America Corp DE 2,785 $6  12/31/2023      VYNE 2,785 $6  12/31/2023 Morgan Stanley 1,868 $4  12/31/2023      VYNE 1,868 $4  12/31/2023 Royal Bank of Canada 1,265 $3  12/31/2023      VYNE 1,265 $3  12/31/2023 Tower Research Capital LLC TRC 790 $2  12/31/2023      VYNE 790 $2  12/31/2023 UBS Group AG 846 $2  12/31/2023      VYNE 846 $2  12/31/2023 JPMorgan Chase & Co. 146 $0  12/31/2023      VYNE 146 $0  12/31/2023 Wells Fargo & Company MN 172 $0  12/31/2023      VYNE 172 $0  12/31/2023 Proequities Inc.   $0  12/31/2023      Put 0 $0  12/31/2023      Call 0 $0  12/31/2023      VYNE 0 $0  12/31/2023      COM 0 $0  12/31/2023 Russell Investments Group Ltd. 187 $0  12/31/2023      VYNE 187 $0  12/31/2023 See All: Funds Holding VYNE See Details: Top 10 Hedge Funds Holding VYNE Also See: VYNE Insider Buying Also See: VYNE Holdings Changes

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