There is a long list of 136 institutional holders of PLRX within the last two holding periods in our database of 13F filers, so we've sorted through to present to you just the top 50 institutional holders of PLRX by largest to smallest position reported in the institutional investor's latest 13F filing. In the institutional-holders-of-PLRX table below, the initial column indicates the name of each top institutional holder of PLRX, with a link to that fund's top holdings. The next columns indicate the amount of PLRX stock held by each of the institutional holders of PLRX, followed by the PLRX position size held by the institution, and finally the date of the quarterly 13F filing period the holdings data represents for that institution.

Holder	Amount	Position Size ($ in 1000's)	As of
Deep Track Capital LP	5,750,000	$104,132	12/31/2023
PLRX	5,750,000	$104,132	12/31/2023
BlackRock Inc.	4,801,517	$86,955	12/31/2023
PLRX	4,801,517	$86,955	12/31/2023
FMR LLC	3,963,418	$71,777	12/31/2023
PLRX	3,963,418	$71,777	12/31/2023
Price T Rowe Associates Inc. MD	3,785,916	$68,564	12/31/2023
PLRX	3,785,916	$68,564	12/31/2023
First Light Asset Management LLC	3,591,776	$65,047	12/31/2023
PLRX	3,591,776	$65,047	12/31/2023
Laurion Capital Management LP	3,583,567	$64,898	12/31/2023
PLRX	3,583,567	$64,898	12/31/2023
Vanguard Group Inc.	3,065,869	$55,523	12/31/2023
PLRX	3,065,869	$55,523	12/31/2023
Blue Owl Capital Holdings LP	3,004,199	$54,406	12/31/2023
PLRX	3,004,199	$54,406	12/31/2023
Redmile Group LLC	2,696,648	$48,836	12/31/2023
PLRX	2,696,648	$48,836	12/31/2023
TRV GP IV LLC	2,132,867	$38,626	12/31/2023
PLRX	2,132,867	$38,626	12/31/2023
Polar Capital Holdings Plc	2,015,000	$36,492	12/31/2023
PLRX	2,015,000	$36,492	12/31/2023
Great Point Partners LLC	1,823,184	$33,018	12/31/2023
PLRX	1,823,184	$33,018	12/31/2023
Franklin Resources Inc.	1,579,572	$28,606	12/31/2023
PLRX	1,579,572	$28,606	12/31/2023
Casdin Capital LLC	1,577,108	$28,561	12/31/2023
PLRX	1,577,108	$28,561	12/31/2023
Citadel Advisors LLC		$28,232	12/31/2023
PLRX	1,578,514	$28,587	12/31/2023
Put	39,000	$706	12/31/2023
Call	19,400	$351	12/31/2023
State Street Corp	1,335,278	$24,182	12/31/2023
PLRX	1,335,278	$24,182	12/31/2023
Pictet Asset Management Holding SA	1,318,804	$23,884	12/31/2023
PLRX	1,318,804	$23,884	12/31/2023
RA Capital Management L.P.	1,281,000	$23,199	12/31/2023
PLRX	1,281,000	$23,199	12/31/2023
Geode Capital Management LLC	1,187,198	$21,503	12/31/2023
PLRX	1,187,198	$21,503	12/31/2023
Granahan Investment Management Inc. MA	1,150,766	$20,840	12/31/2023
PLRX	1,150,766	$20,840	12/31/2023
Deutsche Bank AG	984,992	$17,838	12/31/2023
PLRX	984,992	$17,838	12/31/2023
Capital International Investors	912,467	$16,525	12/31/2023
PLRX	912,467	$16,525	12/31/2023
Bessemer Group Inc.	532,079	$9,636	12/31/2023
PLRX	532,079	$9,636	12/31/2023
Northern Trust Corp	505,326	$9,151	12/31/2023
PLRX	505,326	$9,151	12/31/2023
Candriam Luxembourg S.C.A.	453,000	$8,204	12/31/2023
PLRX	453,000	$8,204	12/31/2023
Charles Schwab Investment Management Inc.	424,196	$7,682	12/31/2023
PLRX	424,196	$7,682	12/31/2023
Fernwood Investment Management LLC	423,177	$7,664	12/31/2023
PLRX	423,177	$7,664	12/31/2023
Morgan Stanley	405,023	$7,335	12/31/2023
PLRX	405,023	$7,335	12/31/2023
Goldman Sachs Group Inc.	387,246	$7,013	12/31/2023
PLRX	387,246	$7,013	12/31/2023
Rock Springs Capital Management LP	384,996	$6,972	12/31/2023
PLRX	384,996	$6,972	12/31/2023
Ameriprise Financial Inc.	369,801	$6,697	12/31/2023
PLRX	369,801	$6,697	12/31/2023
Barclays PLC	352,897	$6,390	12/31/2023
PLRX	352,897	$6,390	12/31/2023
AXA S.A.	347,100	$6,286	12/31/2023
PLRX	347,100	$6,286	12/31/2023
UBS Group AG	342,173	$6,197	12/31/2023
PLRX	342,173	$6,197	12/31/2023
TRV GP Iii LLC	339,160	$6,142	12/31/2023
PLRX	339,160	$6,142	12/31/2023
Silverarc Capital Management LLC	318,524	$5,768	12/31/2023
PLRX	318,524	$5,768	12/31/2023
ArrowMark Colorado Holdings LLC	281,189	$5,092	12/31/2023
PLRX	281,189	$5,092	12/31/2023
Mass General Brigham Inc	288,690	$4,301	03/31/2024
PLRX	288,690	$4,301	03/31/2024
Bank of New York Mellon Corp	210,640	$3,815	12/31/2023
PLRX	210,640	$3,815	12/31/2023
Sphera Funds Management LTD.	193,554	$3,505	12/31/2023
PLRX	193,554	$3,505	12/31/2023
Nuveen Asset Management LLC	190,736	$3,454	12/31/2023
PLRX	190,736	$3,454	12/31/2023
Dimensional Fund Advisors LP	154,072	$2,790	12/31/2023
PLRX	154,072	$2,790	12/31/2023
Woodline Partners LP	124,090	$2,247	12/31/2023
PLRX	124,090	$2,247	12/31/2023
Fred Alger Management LLC	121,787	$2,206	12/31/2023
PLRX	121,787	$2,206	12/31/2023
Rhenman & Partners Asset Management AB	112,741	$2,042	12/31/2023
PLRX	112,741	$2,042	12/31/2023
TD Asset Management Inc.	112,248	$2,033	12/31/2023
PLRX	112,248	$2,033	12/31/2023
Bond & Devick Financial Network Inc.	100,160	$1,814	12/31/2023
PLRX	100,160	$1,814	12/31/2023
Artia Global Partners LP	100,000	$1,811	12/31/2023
PLRX	100,000	$1,811	12/31/2023
Two Sigma Advisers LP	92,600	$1,677	12/31/2023
PLRX	92,600	$1,677	12/31/2023
Swiss National Bank	88,400	$1,601	12/31/2023
PLRX	88,400	$1,601	12/31/2023