There is a long list of 204 institutional holders of INVA within the last two holding periods in our database of 13F filers, so we've sorted through to present to you just the top 50 institutional holders of INVA by largest to smallest position reported in the institutional investor's latest 13F filing. In the institutional-holders-of-INVA table below, the initial column indicates the name of each top institutional holder of INVA, with a link to that fund's top holdings. The next columns indicate the amount of INVA stock held by each of the institutional holders of INVA, followed by the INVA position size held by the institution, and finally the date of the quarterly 13F filing period the holdings data represents for that institution.

Holder	Amount	Position Size ($ in 1000's)	As of
Opti Capital Management LP		$32,475,000	12/31/2023
NOTE 2	30,000,000	$32,475,000	12/31/2023
BlackRock Inc.		$167,487	12/31/2023
INVA	10,352,073	$166,047	12/31/2023
NOTE 2	1,650,000	$1,440	12/31/2023
Sarissa Capital Management LP	7,277,000	$116,723	12/31/2023
INVA	7,277,000	$116,723	12/31/2023
Vanguard Group Inc.	6,712,443	$107,668	12/31/2023
INVA	6,712,443	$107,668	12/31/2023
Putnam Investments LLC		$105,332	12/31/2023
INVA	6,270,413	$100,577	12/31/2023
CONV	4,410,000	$4,755	12/31/2023
Dimensional Fund Advisors LP	4,516,999	$72,454	12/31/2023
INVA	4,516,999	$72,454	12/31/2023
Renaissance Technologies LLC	4,144,447	$66,477	12/31/2023
INVA	4,144,447	$66,477	12/31/2023
Westfield Capital Management Co. LP	2,614,127	$41,931	12/31/2023
INVA	2,614,127	$41,931	12/31/2023
State Street Corp	2,518,778	$40,401	12/31/2023
INVA	2,518,778	$40,401	12/31/2023
Systematic Financial Management LP	2,165,911	$34,741	12/31/2023
INVA	2,165,911	$34,741	12/31/2023
Morgan Stanley	2,117,157	$33,959	12/31/2023
INVA	2,117,157	$33,959	12/31/2023
Pacer Advisors Inc.	1,728,984	$27,733	12/31/2023
INVA	1,728,984	$27,733	12/31/2023
TENOR CAPITAL MANAGEMENT Co. L.P.		$26,221	12/31/2023
NOTE 2	24,076,000	$26,221	12/31/2023
Geode Capital Management LLC	1,311,272	$21,035	12/31/2023
INVA	1,311,272	$21,035	12/31/2023
Highbridge Capital Management LLC		$20,127	12/31/2023
BOND	23,135,000	$20,127	12/31/2023
Invesco Ltd.	1,154,972	$18,526	12/31/2023
INVA	1,154,972	$18,526	12/31/2023
Goldman Sachs Group Inc.		$16,992	12/31/2023
INVA	1,031,631	$16,547	12/31/2023
CNV	510,000	$445	12/31/2023
Russell Investments Group Ltd.		$15,853	12/31/2023
INVA	869,338	$13,944	12/31/2023
Sovereign Corporate	2,156,000	$1,909	12/31/2023
III Capital Management		$15,199	12/31/2023
NOTE 2	14,000,000	$15,199	12/31/2023
Charles Schwab Investment Management Inc.	933,259	$14,969	12/31/2023
INVA	933,259	$14,969	12/31/2023
Deutsche Bank AG		$13,357	12/31/2023
INVA	719,505	$11,541	12/31/2023
Call	113,200	$1,816	12/31/2023
Assenagon Asset Management S.A.	810,208	$12,996	12/31/2023
INVA	810,208	$12,996	12/31/2023
Bank of America Corp DE	797,068	$12,785	12/31/2023
INVA	797,068	$12,785	12/31/2023
CNH Partners LLC		$12,525	12/31/2023
NOTE 2	14,273,000	$12,525	12/31/2023
D. E. Shaw & Co. Inc.	771,018	$12,367	12/31/2023
INVA	771,018	$12,367	12/31/2023
Northern Trust Corp	721,173	$11,568	12/31/2023
INVA	721,173	$11,568	12/31/2023
Bank of New York Mellon Corp		$9,687	12/31/2023
INVA	593,072	$9,513	12/31/2023
NOTE	200,000	$174	12/31/2023
Bridgeway Capital Management Inc.	520,126	$8,343	12/31/2023
INVA	520,126	$8,343	12/31/2023
Nuveen Asset Management LLC	483,639	$7,758	12/31/2023
INVA	483,639	$7,758	12/31/2023
Robeco Institutional Asset Management B.V.	478,623	$7,677	12/31/2023
INVA	478,623	$7,677	12/31/2023
JPMorgan Chase & Co.		$7,023	12/31/2023
INVA	329,207	$5,280	12/31/2023
BOND	2,003,000	$1,743	12/31/2023
CSS LLC IL		$6,089	12/31/2023
NOTE 2	6,920,000	$6,089	12/31/2023
Man Group plc	378,416	$6,070	12/31/2023
INVA	378,416	$6,070	12/31/2023
Two Sigma Investments LP	370,914	$5,949	12/31/2023
INVA	370,914	$5,949	12/31/2023
Norges Bank	369,413	$5,925	12/31/2023
INVA	369,413	$5,925	12/31/2023
Context Capital Management LLC		$5,749	12/31/2023
NOTE 2	6,551,000	$5,749	12/31/2023
UBS Group AG	357,659	$5,737	12/31/2023
INVA	357,659	$5,737	12/31/2023
Principal Financial Group Inc.	322,870	$5,179	12/31/2023
INVA	322,870	$5,179	12/31/2023
Denali Advisors LLC	326,086	$4,970	03/31/2024
INVA	326,086	$4,970	03/31/2024
Hillsdale Investment Management Inc.	290,700	$4,663	12/31/2023
INVA	290,700	$4,663	12/31/2023
Citadel Advisors LLC		$4,387	12/31/2023
INVA	281,804	$4,520	12/31/2023
Put	11,700	$188	12/31/2023
Call	3,400	$55	12/31/2023
Comerica Bank	261,549	$4,195	12/31/2023
INVA	261,549	$4,195	12/31/2023
LSV Asset Management	255,500	$4,098	12/31/2023
INVA	255,500	$4,098	12/31/2023
CWA Asset Management Group LLC	253,759	$4,070	12/31/2023
INVA	253,759	$4,070	12/31/2023
Arrowstreet Capital Limited Partnership	232,219	$3,725	12/31/2023
INVA	232,219	$3,725	12/31/2023
Empowered Funds LLC	230,936	$3,704	12/31/2023
INVA	230,936	$3,704	12/31/2023
Two Sigma Advisers LP	211,000	$3,384	12/31/2023
INVA	211,000	$3,384	12/31/2023
Rhumbline Advisers	208,536	$3,345	12/31/2023
INVA	208,536	$3,345	12/31/2023
Boston Partners	205,672	$3,299	12/31/2023
INVA	205,672	$3,299	12/31/2023
Redwood Investment Management LLC	200,622	$3,218	12/31/2023
INVA	200,622	$3,218	12/31/2023