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Holder Amount Position Size ($ in 1000's)  As of RA Capital Management L.P. 6,144,881 $23,719  12/31/2023      HOWL 6,144,881 $23,719  12/31/2023 MPM Asset Management LLC 4,284,172 $16,537  12/31/2023      HOWL 4,284,172 $16,537  12/31/2023 PFM Health Sciences LP 3,468,177 $13,387  12/31/2023      HOWL 3,468,177 $13,387  12/31/2023 Adage Capital Partners GP L.L.C. 3,034,255 $11,712  12/31/2023      HOWL 3,034,255 $11,712  12/31/2023 MPM Oncology Impact Management LP 2,388,011 $9,218  12/31/2023      HOWL 2,388,011 $9,218  12/31/2023 Bank of America Corp DE 2,096,081 $8,091  12/31/2023      HOWL 2,096,081 $8,091  12/31/2023 Rubric Capital Management LP 1,935,357 $7,470  12/31/2023      HOWL 1,935,357 $7,470  12/31/2023 Vanguard Group Inc. 873,438 $3,371  12/31/2023      HOWL 873,438 $3,371  12/31/2023 Sphera Funds Management LTD. 626,810 $2,419  12/31/2023      HOWL 626,810 $2,419  12/31/2023 DC Funds LP 589,102 $2,274  12/31/2023      HOWL 589,102 $2,274  12/31/2023 Millennium Management LLC 444,359 $1,715  12/31/2023      HOWL 444,359 $1,715  12/31/2023 Alyeska Investment Group L.P. 435,705 $1,682  12/31/2023      HOWL 435,705 $1,682  12/31/2023 Geode Capital Management LLC 194,308 $750  12/31/2023      HOWL 194,308 $750  12/31/2023 Two Sigma Advisers LP 177,300 $684  12/31/2023      HOWL 177,300 $684  12/31/2023 Two Sigma Investments LP 146,736 $566  12/31/2023      HOWL 146,736 $566  12/31/2023 Renaissance Technologies LLC 107,506 $415  12/31/2023      HOWL 107,506 $415  12/31/2023 Bridgeway Capital Management Inc. 85,086 $328  12/31/2023      HOWL 85,086 $328  12/31/2023 State Street Corp 83,468 $322  12/31/2023      HOWL 83,468 $322  12/31/2023 Laurion Capital Management LP 79,213 $306  12/31/2023      HOWL 79,213 $306  12/31/2023 Acadian Asset Management LLC 78,671 $303  12/31/2023      HOWL 78,671 $303  12/31/2023 BlackRock Inc. 72,228 $279  12/31/2023      HOWL 72,228 $279  12/31/2023 Dimensional Fund Advisors LP 62,923 $243  12/31/2023      HOWL 62,923 $243  12/31/2023 Edgewood Management LLC 50,000 $193  12/31/2023      HOWL 50,000 $193  12/31/2023 Northern Trust Corp 49,648 $192  12/31/2023      HOWL 49,648 $192  12/31/2023 Denali Advisors LLC 26,600 $172  03/31/2024      HOWL 26,600 $172  03/31/2024 HBK Sorce Advisory LLC 26,454 $102  12/31/2023      HOWL 26,454 $102  12/31/2023 Citadel Advisors LLC   $97  12/31/2023      HOWL 21,522 $83  12/31/2023      Call 3,700 $14  12/31/2023      Put 100 $0  12/31/2023 Lighthouse Investment Partners LLC 22,472 $87  12/31/2023      HOWL 22,472 $87  12/31/2023 Virtu Financial LLC 20,383 $79  12/31/2023      HOWL 20,383 $79  12/31/2023 Prudential Financial Inc. 15,400 $59  12/31/2023      HOWL 15,400 $59  12/31/2023 Susquehanna International Group LLP 14,777 $57  12/31/2023      HOWL 14,777 $57  12/31/2023 Jane Street Group LLC 14,487 $56  12/31/2023      HOWL 14,487 $56  12/31/2023 Camden Capital LLC 10,000 $39  12/31/2023      HOWL 10,000 $39  12/31/2023 Financial Perspectives Inc 6,750 $26  12/31/2023      HOWL 6,750 $26  12/31/2023 Simplex Trading LLC   $21  12/31/2023      HOWL 5,698 $21  12/31/2023      Call 200 $0  12/31/2023 Qube Research & Technologies Ltd 2,384 $9  12/31/2023      HOWL 2,384 $9  12/31/2023 UBS Group AG 1,000 $4  12/31/2023      HOWL 1,000 $4  12/31/2023 Morgan Stanley 600 $2  12/31/2023      HOWL 600 $2  12/31/2023 Wells Fargo & Company MN 154 $1  12/31/2023      HOWL 154 $1  12/31/2023 Baystate Wealth Management LLC 300 $1  12/31/2023      HOWL 300 $1  12/31/2023 JPMorgan Chase & Co. 83 $0  12/31/2023      HOWL 83 $0  12/31/2023 Proequities Inc.   $0  12/31/2023      Put 0 $0  12/31/2023      Call 0 $0  12/31/2023      HOWL 0 $0  12/31/2023 See All: Funds Holding HOWL See Details: Top 10 Hedge Funds Holding HOWL Also See: HOWL Insider Buying Also See: HOWL Holdings Changes

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