There is a long list of 422 institutional holders of EXEL within the last two holding periods in our database of 13F filers, so we've sorted through to present to you just the top 50 institutional holders of EXEL by largest to smallest position reported in the institutional investor's latest 13F filing. In the institutional-holders-of-EXEL table below, the initial column indicates the name of each top institutional holder of EXEL, with a link to that fund's top holdings. The next columns indicate the amount of EXEL stock held by each of the institutional holders of EXEL, followed by the EXEL position size held by the institution, and finally the date of the quarterly 13F filing period the holdings data represents for that institution.

Holder	Amount	Position Size ($ in 1000's)	As of
BlackRock Inc.	36,014,432	$863,986	12/31/2023
EXEL	36,014,432	$863,986	12/31/2023
Vanguard Group Inc.	31,671,090	$759,789	12/31/2023
EXEL	31,671,090	$759,789	12/31/2023
Farallon Capital Management LLC	26,634,500	$638,962	12/31/2023
EXEL	26,634,500	$638,962	12/31/2023
Renaissance Technologies LLC	15,615,716	$374,621	12/31/2023
EXEL	15,615,716	$374,621	12/31/2023
State Street Corp	13,032,818	$312,657	12/31/2023
EXEL	13,032,818	$312,657	12/31/2023
JPMorgan Chase & Co.		$185,757	12/31/2023
EXEL	7,741,589	$185,721	12/31/2023
Call	1,500	$36	12/31/2023
Geode Capital Management LLC	5,145,318	$123,455	12/31/2023
EXEL	5,145,318	$123,455	12/31/2023
Morgan Stanley	4,774,731	$114,546	12/31/2023
EXEL	4,774,731	$114,546	12/31/2023
Dimensional Fund Advisors LP	4,560,517	$109,409	12/31/2023
EXEL	4,560,517	$109,409	12/31/2023
Stephens Investment Management Group LLC	4,106,664	$98,519	12/31/2023
EXEL	4,106,664	$98,519	12/31/2023
Price T Rowe Associates Inc. MD	3,649,673	$87,556	12/31/2023
EXEL	3,649,673	$87,556	12/31/2023
Nuveen Asset Management LLC	3,478,859	$83,458	12/31/2023
EXEL	3,478,859	$83,458	12/31/2023
Charles Schwab Investment Management Inc.	3,364,480	$80,714	12/31/2023
EXEL	3,364,480	$80,714	12/31/2023
First Trust Advisors LP	3,152,755	$75,635	12/31/2023
EXEL	3,152,755	$75,635	12/31/2023
FMR LLC	3,072,019	$73,698	12/31/2023
EXEL	3,072,019	$73,698	12/31/2023
Norges Bank	3,061,647	$73,449	12/31/2023
EXEL	3,061,647	$73,449	12/31/2023
Bank of New York Mellon Corp	2,775,519	$65,863	03/31/2024
EXEL	2,775,519	$65,863	03/31/2024
Fuller & Thaler Asset Management Inc.	2,615,300	$62,741	12/31/2023
EXEL	2,615,300	$62,741	12/31/2023
Point72 Asset Management L.P.		$62,292	12/31/2023
Call	2,596,600	$62,292	12/31/2023
Los Angeles Capital Management & Equity Research Inc.	2,454,277	$58,240	03/31/2024
EXEL	2,454,277	$58,240	03/31/2024
Jacobs Levy Equity Management Inc.	2,364,913	$56,734	12/31/2023
EXEL	2,364,913	$56,734	12/31/2023
Pictet Asset Management Holding SA	2,224,909	$53,376	12/31/2023
EXEL	2,224,909	$53,376	12/31/2023
Northern Trust Corp	2,218,833	$53,230	12/31/2023
EXEL	2,218,833	$53,230	12/31/2023
AQR Capital Management LLC	2,178,705	$52,267	12/31/2023
EXEL	2,178,705	$52,267	12/31/2023
Meditor Group Ltd	2,198,800	$52,178	03/31/2024
EXEL	2,198,800	$52,178	03/31/2024
Bellevue Group AG	2,108,100	$50,573	12/31/2023
EXEL	2,108,100	$50,573	12/31/2023
California Public Employees Retirement System	1,974,291	$47,363	12/31/2023
EXEL	1,974,291	$47,363	12/31/2023
Krensavage Asset Management LLC	1,899,079	$45,559	12/31/2023
EXEL	1,899,079	$45,559	12/31/2023
Ameriprise Financial Inc.	1,859,026	$44,598	12/31/2023
EXEL	1,859,026	$44,598	12/31/2023
Two Sigma Advisers LP	1,840,490	$44,153	12/31/2023
EXEL	1,840,490	$44,153	12/31/2023
Acadian Asset Management LLC	1,772,177	$42,482	12/31/2023
EXEL	1,772,177	$42,482	12/31/2023
Invesco Ltd.	1,768,592	$42,429	12/31/2023
EXEL	1,768,592	$42,429	12/31/2023
Assenagon Asset Management S.A.	1,766,602	$41,921	03/31/2024
EXEL	1,766,602	$41,921	03/31/2024
Bank of America Corp DE		$41,388	12/31/2023
EXEL	1,591,432	$38,178	12/31/2023
Call	288,100	$6,912	12/31/2023
Put	154,300	$3,702	12/31/2023
Russell Investments Group Ltd.	1,513,591	$36,314	12/31/2023
EXEL	1,513,591	$36,314	12/31/2023
Millennium Management LLC	1,483,172	$35,581	12/31/2023
EXEL	1,483,172	$35,581	12/31/2023
Brandywine Global Investment Management LLC	1,433,915	$34,400	12/31/2023
EXEL	1,433,915	$34,400	12/31/2023
Allspring Global Investments Holdings LLC	1,278,910	$30,349	03/31/2024
EXEL	1,278,910	$30,349	03/31/2024
Samlyn Capital LLC		$29,026	12/31/2023
Call	1,209,900	$29,026	12/31/2023
PSquared Asset Management AG		$29,023	12/31/2023
EXEL	1,390,915	$30,514	12/31/2023
Put	14,000	$1,491	12/31/2023
Principal Financial Group Inc.	1,151,939	$27,635	12/31/2023
EXEL	1,151,939	$27,635	12/31/2023
Systematic Financial Management LP	1,135,311	$27,236	12/31/2023
EXEL	1,135,311	$27,236	12/31/2023
Goldman Sachs Group Inc.	1,048,809	$25,161	12/31/2023
EXEL	1,048,809	$25,161	12/31/2023
Woodline Partners LP	987,094	$23,680	12/31/2023
EXEL	987,094	$23,680	12/31/2023
Citadel Advisors LLC		$23,000	12/31/2023
EXEL	624,648	$14,985	12/31/2023
Call	474,100	$11,374	12/31/2023
Put	140,000	$3,359	12/31/2023
Rhumbline Advisers	944,776	$22,665	12/31/2023
EXEL	944,776	$22,665	12/31/2023
Jupiter Asset Management Ltd.	913,832	$21,923	12/31/2023
EXEL	913,832	$21,923	12/31/2023
Caligan Partners LP	910,730	$21,848	12/31/2023
EXEL	910,730	$21,848	12/31/2023
Prudential Financial Inc.	870,886	$20,893	12/31/2023
EXEL	870,886	$20,893	12/31/2023
D. E. Shaw & Co. Inc.	854,140	$20,491	12/31/2023
EXEL	854,140	$20,491	12/31/2023