There is a long list of 160 institutional holders of AVXL within the last two holding periods in our database of 13F filers, so we've sorted through to present to you just the top 50 institutional holders of AVXL by largest to smallest position reported in the institutional investor's latest 13F filing. In the institutional-holders-of-AVXL table below, the initial column indicates the name of each top institutional holder of AVXL, with a link to that fund's top holdings. The next columns indicate the amount of AVXL stock held by each of the institutional holders of AVXL, followed by the AVXL position size held by the institution, and finally the date of the quarterly 13F filing period the holdings data represents for that institution.

Holder	Amount	Position Size ($ in 1000's)	As of
BlackRock Inc.	6,671,075	$62,108	12/31/2023
AVXL	6,671,075	$62,108	12/31/2023
Vanguard Group Inc.	4,360,648	$40,598	12/31/2023
AVXL	4,360,648	$40,598	12/31/2023
State Street Corp	3,642,702	$33,914	12/31/2023
AVXL	3,642,702	$33,914	12/31/2023
Geode Capital Management LLC	1,665,364	$15,506	12/31/2023
AVXL	1,665,364	$15,506	12/31/2023
Nwam LLC	798,293	$7,432	12/31/2023
AVXL	798,293	$7,432	12/31/2023
Northern Trust Corp	741,425	$6,903	12/31/2023
AVXL	741,425	$6,903	12/31/2023
Charles Schwab Investment Management Inc.	622,310	$5,794	12/31/2023
AVXL	622,310	$5,794	12/31/2023
Morgan Stanley	452,203	$4,210	12/31/2023
AVXL	452,203	$4,210	12/31/2023
Citadel Advisors LLC		$3,853	12/31/2023
Call	281,800	$2,624	12/31/2023
AVXL	273,310	$2,545	12/31/2023
Put	141,400	$1,316	12/31/2023
Susquehanna International Group LLP		$3,399	12/31/2023
AVXL	721,353	$6,716	12/31/2023
Put	648,300	$6,036	12/31/2023
Call	292,000	$2,719	12/31/2023
SG Americas Securities LLC	307,568	$2,863	12/31/2023
AVXL	307,568	$2,863	12/31/2023
Goldman Sachs Group Inc.	266,573	$2,482	12/31/2023
AVXL	266,573	$2,482	12/31/2023
Simplex Trading LLC		$2,439	12/31/2023
Call	231,600	$2,156	12/31/2023
AVXL	72,136	$671	12/31/2023
Put	41,700	$388	12/31/2023
Bank of New York Mellon Corp	256,098	$2,384	12/31/2023
AVXL	256,098	$2,384	12/31/2023
Nuveen Asset Management LLC	240,441	$2,239	12/31/2023
AVXL	240,441	$2,239	12/31/2023
Rafferty Asset Management LLC	232,031	$2,160	12/31/2023
AVXL	232,031	$2,160	12/31/2023
Barclays PLC	210,430	$1,959	12/31/2023
AVXL	210,430	$1,959	12/31/2023
Bank of America Corp DE	204,938	$1,908	12/31/2023
AVXL	204,938	$1,908	12/31/2023
UBS Group AG		$1,725	12/31/2023
AVXL	205,285	$1,911	12/31/2023
Put	20,000	$186	12/31/2023
Swiss National Bank	161,500	$1,504	12/31/2023
AVXL	161,500	$1,504	12/31/2023
Group One Trading L.P.		$1,343	12/31/2023
Call	219,800	$2,046	12/31/2023
Put	78,400	$730	12/31/2023
AVXL	2,935	$27	12/31/2023
State of Wisconsin Investment Board	136,834	$1,274	12/31/2023
AVXL	136,834	$1,274	12/31/2023
BNP Paribas Arbitrage SA	111,032	$1,034	12/31/2023
AVXL	111,032	$1,034	12/31/2023
Jupiter Asset Management Ltd.	103,830	$967	12/31/2023
AVXL	103,830	$967	12/31/2023
Citigroup Inc.	102,688	$956	12/31/2023
AVXL	102,688	$956	12/31/2023
Rhumbline Advisers	100,424	$935	12/31/2023
AVXL	100,424	$935	12/31/2023
Credit Suisse AG	97,464	$907	12/31/2023
AVXL	97,464	$907	12/31/2023
UBS Asset Management Americas Inc.	96,924	$902	12/31/2023
AVXL	96,924	$902	12/31/2023
Jane Street Group LLC		$882	12/31/2023
AVXL	112,310	$1,046	12/31/2023
Put	89,000	$829	12/31/2023
Call	71,400	$665	12/31/2023
Commonwealth Equity Services LLC	91,790	$855	12/31/2023
AVXL	91,790	$855	12/31/2023
Alliancebernstein L.P.	88,040	$820	12/31/2023
AVXL	88,040	$820	12/31/2023
Hikari Power Ltd	85,585	$797	12/31/2023
AVXL	85,585	$797	12/31/2023
California State Teachers Retirement System	84,885	$790	12/31/2023
AVXL	84,885	$790	12/31/2023
Carnegie Capital Asset Management LLC	73,660	$686	12/31/2023
AVXL	73,660	$686	12/31/2023
Legal & General Group Plc	71,273	$664	12/31/2023
AVXL	71,273	$664	12/31/2023
Balyasny Asset Management LLC	69,301	$645	12/31/2023
AVXL	69,301	$645	12/31/2023
Wells Fargo & Company MN	68,146	$634	12/31/2023
AVXL	68,146	$634	12/31/2023
Geneos Wealth Management Inc.	67,600	$629	12/31/2023
AVXL	67,600	$629	12/31/2023
JPMorgan Chase & Co.	64,436	$600	12/31/2023
AVXL	64,436	$600	12/31/2023
Jump Financial LLC	60,986	$568	12/31/2023
AVXL	60,986	$568	12/31/2023
Cetera Advisor Networks LLC	59,664	$555	12/31/2023
AVXL	59,664	$555	12/31/2023
LPL Financial LLC	58,880	$548	12/31/2023
AVXL	58,880	$548	12/31/2023
Trexquant Investment LP	57,655	$537	12/31/2023
AVXL	57,655	$537	12/31/2023
Alps Advisors Inc.	56,131	$523	12/31/2023
AVXL	56,131	$523	12/31/2023
Ameriprise Financial Inc.	54,652	$509	12/31/2023
AVXL	54,652	$509	12/31/2023
D. E. Shaw & Co. Inc.	53,454	$498	12/31/2023
AVXL	53,454	$498	12/31/2023
AllSquare Wealth Management LLC	53,456	$498	12/31/2023
AVXL	53,456	$498	12/31/2023
Cubist Systematic Strategies LLC	50,993	$475	12/31/2023
AVXL	50,993	$475	12/31/2023
Price T Rowe Associates Inc. MD	50,828	$474	12/31/2023
AVXL	50,828	$474	12/31/2023
Dimensional Fund Advisors LP	49,596	$462	12/31/2023
AVXL	49,596	$462	12/31/2023