On this page, we present all of the funds holding SNCE from our database of 13F filers, detailed in the table below. The first column indicates the name of each of the funds holding SNCE, with a link to that fund's top holdings. The next columns indicate the amount of SNCE stock held by each of the funds holding SNCE, followed by the SNCE position size held by the fund, and lastly the date of the quarterly filing period the data represents. In total, we count 67 funds holding SNCE within the last two filing periods in our coverage universe of 13F filers, with the largest position size having been reported by Redmile Group LLC. For more details on the positions held by Redmile Group LLC (or by any of the other funds holding SNCE), click the fund name in the "Holder" column of the funds-holding-SNCE table below.

Holder	Amount	Position Size ($ in 1000's)	As of
Redmile Group LLC	19,808,234	$31,891	09/30/2022
SNCE	19,808,234	$31,891	09/30/2022
RTW Investments LP	4,328,387	$6,969	09/30/2022
SNCE	4,328,387	$6,969	09/30/2022
Walleye Capital LLC	4,017,763	$6,469	09/30/2022
SNCE	4,017,763	$6,469	09/30/2022
BlackRock Inc.	3,359,291	$5,408	09/30/2022
SNCE	3,359,291	$5,408	09/30/2022
Vanguard Group Inc.	3,221,621	$5,187	09/30/2022
SNCE	3,221,621	$5,187	09/30/2022
Alphabet Inc.	3,207,260	$5,164	09/30/2022
SNCE	3,207,260	$5,164	09/30/2022
MIC Capital Management UK LLP	2,345,897	$3,777	09/30/2022
SNCE	2,345,897	$3,777	09/30/2022
FMR LLC	1,947,182	$3,135	09/30/2022
SNCE	1,947,182	$3,135	09/30/2022
Perceptive Advisors LLC	1,500,000	$2,415	09/30/2022
SNCE	1,500,000	$2,415	09/30/2022
Citadel Advisors LLC	1,417,440	$2,282	09/30/2022
SNCE	1,417,440	$2,282	09/30/2022
Ally Bridge Group NY LLC	1,266,512	$2,039	09/30/2022
SNCE	1,266,512	$2,039	09/30/2022
Geode Capital Management LLC	1,111,744	$1,789	09/30/2022
SNCE	1,111,744	$1,789	09/30/2022
Pura Vida Investments LLC	1,106,400	$1,781	09/30/2022
SNCE	1,106,400	$1,781	09/30/2022
Alyeska Investment Group L.P.	1,049,006	$1,689	09/30/2022
SNCE	1,049,006	$1,689	09/30/2022
State Street Corp	1,028,506	$1,656	09/30/2022
SNCE	1,028,506	$1,656	09/30/2022
Glynn Capital Management LLC	3,539,824	$1,470	12/31/2022
SNCE	3,539,824	$1,470	12/31/2022
Samsara BioCapital LLC	900,000	$1,449	09/30/2022
SNCE	900,000	$1,449	09/30/2022
Northern Trust Corp	513,544	$826	09/30/2022
SNCE	513,544	$826	09/30/2022
Cowen AND Company LLC	466,267	$751	09/30/2022
SNCE	466,267	$751	09/30/2022
Avidity Partners Management LP	430,000	$692	09/30/2022
SNCE	430,000	$692	09/30/2022
Russell Investments Group Ltd.	279,617	$448	09/30/2022
SNCE	279,617	$448	09/30/2022
Nuveen Asset Management LLC	228,245	$368	09/30/2022
SNCE	228,245	$368	09/30/2022
Bank of New York Mellon Corp	190,824	$307	09/30/2022
SNCE	190,824	$307	09/30/2022
Victory Capital Management Inc.	178,320	$287	09/30/2022
SNCE	178,320	$287	09/30/2022
Boston Partners	137,929	$222	09/30/2022
SNCE	137,929	$222	09/30/2022
Charles Schwab Investment Management Inc.	136,794	$221	09/30/2022
SNCE	136,794	$221	09/30/2022
Renaissance Technologies LLC	100,300	$161	09/30/2022
SNCE	100,300	$161	09/30/2022
Ellevest Inc.	337,408	$140	12/31/2022
SNCE	337,408	$140	12/31/2022
Rhumbline Advisers	79,209	$128	09/30/2022
SNCE	79,209	$128	09/30/2022
Two Sigma Investments LP	63,313	$102	09/30/2022
SNCE	63,313	$102	09/30/2022
Morgan Stanley	61,813	$100	09/30/2022
SNCE	61,813	$100	09/30/2022
Dowling & Yahnke LLC	42,253	$68	09/30/2022
SNCE	42,253	$68	09/30/2022
Invesco Ltd.	34,644	$56	09/30/2022
SNCE	34,644	$56	09/30/2022
JPMorgan Chase & Co.	33,559	$54	09/30/2022
SNCE	33,559	$54	09/30/2022
American International Group Inc.	29,557	$48	09/30/2022
SNCE	29,557	$48	09/30/2022
Mariner LLC	29,857	$48	09/30/2022
SNCE	29,857	$48	09/30/2022
Deutsche Bank AG	27,590	$45	09/30/2022
SNCE	27,590	$45	09/30/2022
California State Teachers Retirement System	24,575	$40	09/30/2022
SNCE	24,575	$40	09/30/2022
Voya Investment Management LLC	23,786	$38	09/30/2022
SNCE	23,786	$38	09/30/2022
Pittenger & Anderson Inc.	21,536	$35	09/30/2022
SNCE	21,536	$35	09/30/2022
Bank of America Corp DE	20,660	$33	09/30/2022
SNCE	20,660	$33	09/30/2022
Susquehanna International Group LLP	18,835	$30	09/30/2022
SNCE	18,835	$30	09/30/2022
Alliancebernstein L.P.	17,200	$28	09/30/2022
SNCE	17,200	$28	09/30/2022
AQR Capital Management LLC	17,158	$28	09/30/2022
SNCE	17,158	$28	09/30/2022
Verition Fund Management LLC	16,637	$27	09/30/2022
SNCE	16,637	$27	09/30/2022
Bienville Capital Management LLC	16,656	$27	09/30/2022
SNCE	16,656	$27	09/30/2022
Goldman Sachs Group Inc.	16,385	$26	09/30/2022
SNCE	16,385	$26	09/30/2022
The Manufacturers Life Insurance Company	15,659	$25	09/30/2022
SNCE	15,659	$25	09/30/2022
Tower Research Capital LLC TRC	15,264	$25	09/30/2022
SNCE	15,264	$25	09/30/2022
The PNC Financial Services Group Inc.	14,140	$22	09/30/2022
SNCE	14,140	$22	09/30/2022
PEAK6 Investments LLC	12,550	$20	09/30/2022
SNCE	12,550	$20	09/30/2022
New York State Common Retirement Fund	44,800	$19	12/31/2022
SNCE	44,800	$19	12/31/2022
Amalgamated Bank	9,792	$16	09/30/2022
SNCE	9,792	$16	09/30/2022
Legal & General Group Plc	6,587	$11	09/30/2022
SNCE	6,587	$11	09/30/2022
Allspring Global Investments Holdings LLC	25,089	$10	12/31/2022
SNCE	25,089	$10	12/31/2022
Rockefeller Capital Management L.P.	5,000	$8	09/30/2022
SNCE	5,000	$8	09/30/2022
Ameritas Investment Partners Inc.	4,669	$7	09/30/2022
SNCE	4,669	$7	09/30/2022
Strs Ohio	14,500	$6	12/31/2022
SNCE	14,500	$6	12/31/2022
SG Americas Securities LLC	15,541	$6	12/31/2022
SNCE	15,541	$6	12/31/2022
Barclays PLC	2,640	$4	09/30/2022
SNCE	2,640	$4	09/30/2022
M&R Capital Management Inc.	7,000	$3	12/31/2022
SNCE	7,000	$3	12/31/2022
Albion Financial Group UT	4,164	$2	12/31/2022
SNCE	4,164	$2	12/31/2022
Wells Fargo & Company MN	1,039	$2	09/30/2022
SNCE	1,039	$2	09/30/2022
Citigroup Inc.	1,276	$2	09/30/2022
SNCE	1,276	$2	09/30/2022
Credit Suisse AG	348	$1	09/30/2022
SNCE	348	$1	09/30/2022
Royal Bank of Canada	758	$1	09/30/2022
SNCE	758	$1	09/30/2022
Proequities Inc.	0	$0	12/31/2022
SNCE	0	$0	12/31/2022
Nisa Investment Advisors LLC	190	$0	12/31/2022
SNCE	190	$0	12/31/2022