On this page, we present all of the funds holding ANNX from our database of 13F filers, detailed in the table below. The first column indicates the name of each of the funds holding ANNX, with a link to that fund's top holdings. The next columns indicate the amount of ANNX stock held by each of the funds holding ANNX, followed by the ANNX position size held by the fund, and lastly the date of the quarterly filing period the data represents. In total, we count 102 funds holding ANNX within the last two filing periods in our coverage universe of 13F filers, with the largest position size having been reported by FMR LLC. For more details on the positions held by FMR LLC (or by any of the other funds holding ANNX), click the fund name in the "Holder" column of the funds-holding-ANNX table below.

Holder	Amount	Position Size ($ in 1000's)	As of
FMR LLC	9,685,401	$43,972	12/31/2023
ANNX	9,685,401	$43,972	12/31/2023
Bain Capital Life Sciences Investors LLC	8,061,719	$36,600	12/31/2023
ANNX	8,061,719	$36,600	12/31/2023
Satter Management CO. L.P.	7,406,024	$33,623	12/31/2023
ANNX	7,406,024	$33,623	12/31/2023
BVF Inc. IL	7,000,000	$31,780	12/31/2023
ANNX	7,000,000	$31,780	12/31/2023
Redmile Group LLC	5,503,190	$24,984	12/31/2023
ANNX	5,503,190	$24,984	12/31/2023
Adage Capital Partners GP L.L.C.	4,999,975	$22,700	12/31/2023
ANNX	4,999,975	$22,700	12/31/2023
Logos Global Management LP	4,950,000	$22,473	12/31/2023
ANNX	4,950,000	$22,473	12/31/2023
BlackRock Inc.	3,318,579	$15,066	12/31/2023
ANNX	3,318,579	$15,066	12/31/2023
GMT Capital Corp	3,020,474	$13,713	12/31/2023
ANNX	3,020,474	$13,713	12/31/2023
Ikarian Capital LLC	2,650,000	$12,031	12/31/2023
ANNX	2,650,000	$12,031	12/31/2023
Octagon Capital Advisors LP	2,050,000	$9,307	12/31/2023
ANNX	2,050,000	$9,307	12/31/2023
Woodline Partners LP	2,000,000	$9,080	12/31/2023
ANNX	2,000,000	$9,080	12/31/2023
Vanguard Group Inc.	1,908,326	$8,664	12/31/2023
ANNX	1,908,326	$8,664	12/31/2023
Pictet Asset Management Holding SA	1,803,149	$8,186	12/31/2023
ANNX	1,803,149	$8,186	12/31/2023
Kennedy Capital Management Inc.	1,075,730	$4,884	12/31/2023
ANNX	1,075,730	$4,884	12/31/2023
Citadel Advisors LLC		$4,834	12/31/2023
ANNX	1,057,687	$4,802	12/31/2023
Call	11,400	$52	12/31/2023
Put	4,400	$20	12/31/2023
Geode Capital Management LLC	922,232	$4,187	12/31/2023
ANNX	922,232	$4,187	12/31/2023
Acadian Asset Management LLC	874,024	$3,966	12/31/2023
ANNX	874,024	$3,966	12/31/2023
State Street Corp	846,274	$3,842	12/31/2023
ANNX	846,274	$3,842	12/31/2023
Millennium Management LLC	811,019	$3,682	12/31/2023
ANNX	811,019	$3,682	12/31/2023
Massachusetts Financial Services Co. MA	777,968	$3,532	12/31/2023
ANNX	777,968	$3,532	12/31/2023
Boothbay Fund Management LLC	707,815	$3,213	12/31/2023
ANNX	707,815	$3,213	12/31/2023
UBS Oconnor LLC	692,928	$3,146	12/31/2023
ANNX	692,928	$3,146	12/31/2023
Sectoral Asset Management Inc	650,911	$2,955	12/31/2023
ANNX	650,911	$2,955	12/31/2023
Vontobel Holding Ltd.	650,911	$2,955	12/31/2023
ANNX	650,911	$2,955	12/31/2023
StemPoint Capital LP	607,100	$2,756	12/31/2023
ANNX	607,100	$2,756	12/31/2023
Deerfield Management Company L.P. Series C	583,913	$2,651	12/31/2023
ANNX	583,913	$2,651	12/31/2023
Soleus Capital Management L.P.	515,400	$2,340	12/31/2023
ANNX	515,400	$2,340	12/31/2023
Renaissance Technologies LLC	484,200	$2,198	12/31/2023
ANNX	484,200	$2,198	12/31/2023
Board of Trustees of The Leland Stanford Junior University	482,550	$2,191	12/31/2023
ANNX	482,550	$2,191	12/31/2023
Silverarc Capital Management LLC	417,429	$1,895	12/31/2023
ANNX	417,429	$1,895	12/31/2023
Walleye Capital LLC	378,279	$1,717	12/31/2023
ANNX	378,279	$1,717	12/31/2023
Northern Trust Corp	367,275	$1,667	12/31/2023
ANNX	367,275	$1,667	12/31/2023
ExodusPoint Capital Management LP	342,939	$1,557	12/31/2023
ANNX	342,939	$1,557	12/31/2023
Goldman Sachs Group Inc.	284,933	$1,294	12/31/2023
ANNX	284,933	$1,294	12/31/2023
Driehaus Capital Management LLC	258,314	$1,173	12/31/2023
ANNX	258,314	$1,173	12/31/2023
Nuveen Asset Management LLC	194,598	$883	12/31/2023
ANNX	194,598	$883	12/31/2023
Morgan Stanley	192,060	$872	12/31/2023
ANNX	192,060	$872	12/31/2023
Barclays PLC	185,331	$841	12/31/2023
ANNX	185,331	$841	12/31/2023
Bridgeway Capital Management Inc.	179,500	$815	12/31/2023
ANNX	179,500	$815	12/31/2023
Deutsche Bank AG	157,002	$713	12/31/2023
ANNX	157,002	$713	12/31/2023
Susquehanna Portfolio Strategies LLC	141,562	$643	12/31/2023
ANNX	141,562	$643	12/31/2023
Bank of New York Mellon Corp	134,277	$610	12/31/2023
ANNX	134,277	$610	12/31/2023
Charles Schwab Investment Management Inc.	123,668	$561	12/31/2023
ANNX	123,668	$561	12/31/2023
Connor Clark & Lunn Investment Management Ltd.	88,091	$400	12/31/2023
ANNX	88,091	$400	12/31/2023
Dimensional Fund Advisors LP	87,047	$395	12/31/2023
ANNX	87,047	$395	12/31/2023
Two Sigma Advisers LP	84,800	$385	12/31/2023
ANNX	84,800	$385	12/31/2023
Prudential Financial Inc.	80,605	$366	12/31/2023
ANNX	80,605	$366	12/31/2023
Lighthouse Investment Partners LLC	67,511	$306	12/31/2023
ANNX	67,511	$306	12/31/2023
Rhumbline Advisers	59,320	$269	12/31/2023
ANNX	59,320	$269	12/31/2023
DNB Asset Management AS	35,911	$257	03/31/2024
ANNX	35,911	$257	03/31/2024
Bank of America Corp DE	51,324	$233	12/31/2023
ANNX	51,324	$233	12/31/2023
UBS Group AG	49,586	$225	12/31/2023
ANNX	49,586	$225	12/31/2023
Virtu Financial LLC	48,614	$221	12/31/2023
ANNX	48,614	$221	12/31/2023
Cornercap Investment Counsel Inc.	46,698	$212	12/31/2023
ANNX	46,698	$212	12/31/2023
Alliancebernstein L.P.	40,620	$184	12/31/2023
ANNX	40,620	$184	12/31/2023
Hsbc Holdings PLC	36,406	$171	12/31/2023
ANNX	36,406	$171	12/31/2023
American Century Companies Inc.	33,864	$154	12/31/2023
ANNX	33,864	$154	12/31/2023
Jane Street Group LLC	31,644	$144	12/31/2023
ANNX	31,644	$144	12/31/2023
Forefront Analytics LLC	31,280	$142	12/31/2023
ANNX	31,280	$142	12/31/2023
JPMorgan Chase & Co.	29,585	$134	12/31/2023
ANNX	29,585	$134	12/31/2023
Algert Global LLC	27,880	$127	12/31/2023
ANNX	27,880	$127	12/31/2023
Two Sigma Investments LP	26,583	$121	12/31/2023
ANNX	26,583	$121	12/31/2023
SG Americas Securities LLC	25,335	$115	12/31/2023
ANNX	25,335	$115	12/31/2023
American International Group Inc.	22,687	$103	12/31/2023
ANNX	22,687	$103	12/31/2023
Invesco Ltd.	21,772	$99	12/31/2023
ANNX	21,772	$99	12/31/2023
Allegheny Financial Group LTD	21,700	$99	12/31/2023
ANNX	21,700	$99	12/31/2023
The Manufacturers Life Insurance Company	20,021	$91	12/31/2023
ANNX	20,021	$91	12/31/2023
Voya Investment Management LLC	19,070	$87	12/31/2023
ANNX	19,070	$87	12/31/2023
Cubist Systematic Strategies LLC	17,144	$78	12/31/2023
ANNX	17,144	$78	12/31/2023
Schonfeld Strategic Advisors LLC	17,000	$77	12/31/2023
ANNX	17,000	$77	12/31/2023
Coastal Bridge Advisors LLC	17,000	$77	12/31/2023
ANNX	17,000	$77	12/31/2023
Wells Fargo & Company MN	16,432	$75	12/31/2023
ANNX	16,432	$75	12/31/2023
Atom Investors LP	15,615	$71	12/31/2023
ANNX	15,615	$71	12/31/2023
Susquehanna International Group LLP		$60	12/31/2023
Put	29,300	$133	12/31/2023
ANNX	23,945	$109	12/31/2023
Call	18,600	$84	12/31/2023
Royal Bank of Canada	12,901	$58	12/31/2023
ANNX	12,901	$58	12/31/2023
Price T Rowe Associates Inc. MD	12,509	$57	12/31/2023
ANNX	12,509	$57	12/31/2023
State Board of Administration of Florida Retirement System	11,857	$54	12/31/2023
ANNX	11,857	$54	12/31/2023
HRT Financial LP	12,012	$54	12/31/2023
ANNX	12,012	$54	12/31/2023
Tower Research Capital LLC TRC	11,924	$54	12/31/2023
ANNX	11,924	$54	12/31/2023
Walleye Trading LLC	10,719	$49	12/31/2023
ANNX	10,719	$49	12/31/2023
Balyasny Asset Management LLC	10,107	$46	12/31/2023
ANNX	10,107	$46	12/31/2023
Cambridge Investment Research Advisors Inc.	10,000	$45	12/31/2023
ANNX	10,000	$45	12/31/2023
Kestra Advisory Services LLC	10,000	$45	12/31/2023
ANNX	10,000	$45	12/31/2023
California State Teachers Retirement System	7,512	$34	12/31/2023
ANNX	7,512	$34	12/31/2023
Citigroup Inc.	7,054	$32	12/31/2023
ANNX	7,054	$32	12/31/2023
Amalgamated Bank	3,981	$18	12/31/2023
ANNX	3,981	$18	12/31/2023
Group One Trading L.P.	3,938	$18	12/31/2023
ANNX	3,938	$18	12/31/2023
Ameritas Investment Partners Inc.	3,769	$17	12/31/2023
ANNX	3,769	$17	12/31/2023
Legal & General Group Plc	3,528	$16	12/31/2023
ANNX	3,528	$16	12/31/2023
Simplex Trading LLC		$11	12/31/2023
ANNX	6,753	$30	12/31/2023
Put	4,200	$19	12/31/2023
Sunbelt Securities Inc.	800	$6	03/31/2024
ANNX	800	$6	03/31/2024
New York State Common Retirement Fund	898	$4	12/31/2023
ANNX	898	$4	12/31/2023
Advisor Group Holdings Inc.	791	$4	12/31/2023
ANNX	791	$4	12/31/2023
Russell Investments Group Ltd.	988	$4	12/31/2023
ANNX	988	$4	12/31/2023
Point72 Middle East FZE	614	$3	12/31/2023
ANNX	614	$3	12/31/2023
Private Wealth Management Group LLC	654	$3	12/31/2023
ANNX	654	$3	12/31/2023
The PNC Financial Services Group Inc.	161	$1	12/31/2023
ANNX	161	$1	12/31/2023
HighMark Wealth Management LLC	300	$1	12/31/2023
ANNX	300	$1	12/31/2023
CWM LLC	17	$0	03/31/2024
ANNX	17	$0	03/31/2024
Proequities Inc.		$0	12/31/2023
Put	0	$0	12/31/2023
ANNX	0	$0	12/31/2023
Call	0	$0	12/31/2023
Nomura Asset Management Co. Ltd.	0	$0	12/31/2023
ANNX	0	$0	12/31/2023
Farther Finance Advisors LLC	1	$0	12/31/2023
ANNX	1	$0	12/31/2023