On this page, we present all of the funds holding AGLE from our database of 13F filers, detailed in the table below. The first column indicates the name of each of the funds holding AGLE, with a link to that fund's top holdings. The next columns indicate the amount of AGLE stock held by each of the funds holding AGLE, followed by the AGLE position size held by the fund, and lastly the date of the quarterly filing period the data represents. In total, we count 55 funds holding AGLE within the last two filing periods in our coverage universe of 13F filers, with the largest position size having been reported by FMR LLC. For more details on the positions held by FMR LLC (or by any of the other funds holding AGLE), click the fund name in the "Holder" column of the funds-holding-AGLE table below.

Holder	Amount	Position Size ($ in 1000's)	As of
FMR LLC	3,785,877	$45,468	12/31/2023
AGLE	3,785,877	$45,468	12/31/2023
Perceptive Advisors LLC	2,606,679	$31,306	12/31/2023
AGLE	2,606,679	$31,306	12/31/2023
VR Adviser LLC	2,372,714	$28,496	12/31/2023
AGLE	2,372,714	$28,496	12/31/2023
RTW Investments LP	2,232,760	$26,815	12/31/2023
AGLE	2,232,760	$26,815	12/31/2023
Deep Track Capital LP	1,952,760	$23,453	12/31/2023
AGLE	1,952,760	$23,453	12/31/2023
Commodore Capital LP	1,884,084	$22,628	12/31/2023
AGLE	1,884,084	$22,628	12/31/2023
Avoro Capital Advisors LLC	1,839,138	$22,088	12/31/2023
AGLE	1,839,138	$22,088	12/31/2023
Adage Capital Partners GP L.L.C.	1,000,000	$12,010	12/31/2023
AGLE	1,000,000	$12,010	12/31/2023
Cormorant Asset Management LP	937,080	$11,254	12/31/2023
AGLE	937,080	$11,254	12/31/2023
EcoR1 Capital LLC	887,076	$10,654	12/31/2023
AGLE	887,076	$10,654	12/31/2023
Driehaus Capital Management LLC	771,902	$9,271	12/31/2023
AGLE	771,902	$9,271	12/31/2023
Franklin Resources Inc.	687,090	$8,252	12/31/2023
AGLE	687,090	$8,252	12/31/2023
BVF Inc. IL	687,080	$8,252	12/31/2023
AGLE	687,080	$8,252	12/31/2023
Wellington Management Group LLP	635,455	$7,632	12/31/2023
AGLE	635,455	$7,632	12/31/2023
University of Notre Dame DU Lac	577,616	$6,937	12/31/2023
AGLE	577,616	$6,937	12/31/2023
HighVista Strategies LLC	577,616	$6,937	12/31/2023
AGLE	577,616	$6,937	12/31/2023
Citadel Advisors LLC		$6,927	12/31/2023
AGLE	576,711	$6,926	12/31/2023
Call	60	$1	12/31/2023
Put	4	$0	12/31/2023
Affinity Asset Advisors LLC	517,554	$6,216	12/31/2023
AGLE	517,554	$6,216	12/31/2023
Braidwell LP	515,000	$6,185	12/31/2023
AGLE	515,000	$6,185	12/31/2023
Global Endowment Management LP	513,436	$6,166	12/31/2023
AGLE	513,436	$6,166	12/31/2023
Polar Capital Holdings Plc	500,000	$6,005	12/31/2023
AGLE	500,000	$6,005	12/31/2023
StemPoint Capital LP	378,766	$4,549	12/31/2023
AGLE	378,766	$4,549	12/31/2023
Fairmount Funds Management LLC	378,421	$4,545	12/31/2023
AGLE	378,421	$4,545	12/31/2023
Boxer Capital LLC	250,000	$3,002	12/31/2023
AGLE	250,000	$3,002	12/31/2023
Suvretta Capital Management LLC	162,395	$1,950	12/31/2023
AGLE	162,395	$1,950	12/31/2023
Logos Global Management LP	150,000	$1,802	12/31/2023
AGLE	150,000	$1,802	12/31/2023
Great Point Partners LLC	125,000	$1,501	12/31/2023
AGLE	125,000	$1,501	12/31/2023
Millennium Management LLC	108,486	$1,303	12/31/2023
AGLE	108,486	$1,303	12/31/2023
Prosight Management LP	55,000	$661	12/31/2023
AGLE	55,000	$661	12/31/2023
Renaissance Technologies LLC	48,536	$583	12/31/2023
AGLE	48,536	$583	12/31/2023
Barclays PLC	45,498	$546	12/31/2023
AGLE	45,498	$546	12/31/2023
Vanguard Group Inc.	39,446	$474	12/31/2023
AGLE	39,446	$474	12/31/2023
Geode Capital Management LLC	30,326	$364	12/31/2023
AGLE	30,326	$364	12/31/2023
Two Sigma Investments LP	28,095	$337	12/31/2023
AGLE	28,095	$337	12/31/2023
ExodusPoint Capital Management LP	26,210	$315	12/31/2023
AGLE	26,210	$315	12/31/2023
Cubist Systematic Strategies LLC	26,150	$314	12/31/2023
AGLE	26,150	$314	12/31/2023
Marshall Wace LLP	20,252	$243	12/31/2023
AGLE	20,252	$243	12/31/2023
Blackstone Group Inc	19,991	$240	12/31/2023
AGLE	19,991	$240	12/31/2023
BlackRock Inc.	19,762	$237	12/31/2023
AGLE	19,762	$237	12/31/2023
Legato Capital Management LLC	11,458	$138	03/31/2024
AGLE	11,458	$138	03/31/2024
Citigroup Inc.	10,297	$124	12/31/2023
AGLE	10,297	$124	12/31/2023
Carlyle Group Inc.	9,620	$116	12/31/2023
AGLE	9,620	$116	12/31/2023
ADAR1 Capital Management LLC	6,440	$77	12/31/2023
AGLE	6,440	$77	12/31/2023
Virtus ETF Advisers LLC	6,239	$75	12/31/2023
AGLE	6,239	$75	12/31/2023
UBS Group AG	3,726	$45	12/31/2023
AGLE	3,726	$45	12/31/2023
Tower Research Capital LLC TRC	2,580	$31	12/31/2023
AGLE	2,580	$31	12/31/2023
Acadian Asset Management LLC	1,169	$14	12/31/2023
AGLE	1,169	$14	12/31/2023
New York State Common Retirement Fund	365	$4	12/31/2023
AGLE	365	$4	12/31/2023
Advisor Group Holdings Inc.	283	$3	12/31/2023
AGLE	283	$3	12/31/2023
IFP Advisors Inc	114	$1	12/31/2023
AGLE	114	$1	12/31/2023
JPMorgan Chase & Co.	41	$0	12/31/2023
AGLE	41	$0	12/31/2023
Wells Fargo & Company MN	23	$0	12/31/2023
AGLE	23	$0	12/31/2023
Proequities Inc.		$0	12/31/2023
Put	0	$0	12/31/2023
AGLE	0	$0	12/31/2023
Call	0	$0	12/31/2023
Morgan Stanley	40	$0	12/31/2023
AGLE	40	$0	12/31/2023
Parallel Advisors LLC	1	$0	12/31/2023
AGLE	1	$0	12/31/2023
Pacific Capital Wealth Advisors Inc.	8	$0	12/31/2023
AGLE	8	$0	12/31/2023